...Mitsuyoshi Yamagata; Mutsumi Tsuchishima; Takashi Saito; Mikihiro Tsutsumi; Joseph George Metabolic dysfunction-associated steatohepatitis (MASH) is always accompanied with hepatic fibrosis that could potentially progress to liver cirrhosis and hepatocellular carcinoma. Employing a rat model, we...

... © 2021 The Author(s). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Alamandine Angiotensin II Hepatic fibrosis NADPH oxidase Oxidative stress...

... © 2020 The Author(s). 2020 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Alamandine Angiotensin II Autophagy Hepatic fibrosis NADPH oxidase...

...Yun Huang; Yang Li; Anni Lou; Guo zhen Wang; Ye Hu; Yijie Zhang; Weichang Huang; Jun Wang; Yue Li; Xintao Zhu; Tingting Chen; Jiayi Lin; Ying Meng; Xu Li Angiotensin II (Ang II) has been reported to aggravate hepatic fibrosis by inducing NADPH oxidase (NOX)-dependent oxidative stress. Alamandine...

... sequence against miR-21 was constructed to reduce miR-21 expression efficiently in vitro and in vivo . Histological and immunohistological examinations were performed to evaluate the inhibitory effects and mechanism of Ad-TuD-21 delivery into carbon tetrachloride (CCl 4 ) induced hepatic fibrosis rats...

...). Adiponectin levels were decreased in patients with NAFLD. In conclusion, adiponectin levels correlate positively with surrogate markers of hepatic fibrosis (transient elastography, fasting serum bile acids and hyaluronate) and are significantly elevated in cases of cirrhosis. Correspondence: Professor...

... ]. angiotensin-(1–7) angiotensin-converting enzyme cirrhosis hepatic fibrosis renin–angiotensin system Immunohistochemical staining for α-SMA, a marker for activated HSCs, was performed on 4 μm sections of paraffin-embedded rat liver tissue-mounted on silane-coated glass slides. Specimens were de...

...Paula MAYORAL; Manuela CRIADO; Froilan HIDALGO; Olga FLORES; Miguel A. ARÉVALO; Nélida ELENO; Angel SÁNCHEZ-RODRÍGUEZ; Jose M. LÓPEZ-NOVOA; Alejandro ESTELLER Hepatic fibrosis or increased liver collagen contents drive functional abnormalities that, when extensive, may be life threatening...