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Keywords: IBD
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Articles

The circadian clock, metabolism, and inflammation—the holy trinity of inflammatory bowel diseases

Open Access
Oren Froy, Yael Weintraub
Journal: Clinical Science
Clin Sci (Lond) (2025) 139 (13): 777–790.
https://doi.org/10.1042/CS20256383
Published: 04 July 2025
...Oren Froy; Yael Weintraub Inflammatory bowel diseases (IBDs), including Crohn’s disease and ulcerative colitis, are characterized by relapsing-remitting immune activation and inflammation within the gastrointestinal tract. The immune system activity displays diurnal variation, which is regulated...
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Includes: Supplementary data
Articles

Primary bile acid shapes peripheral immunity in inflammatory bowel disease-associated primary sclerosing cholangitis

Open Access
André A. Santos, David Pires, Vanda Marques, Nicole Alesina, Elisa Herraez, Pavel Roudnický, Pedro M. Rodrigues, Ana Godinho-Santos, Ana Catarina Bravo, Catarina Gouveia, Susana Saraiva, Luís Correia, Ricardo Crespo, João Pereira da Silva, Marília Cravo, David Potesil, Zbyněk Zdráhal, Jesus M. Banales, Jose J.G. Marin, Joana Torres, Cecília M.P. Rodrigues
Journal: Clinical Science
Clin Sci (Lond) (2025) 139 (12): 703–716.
https://doi.org/10.1042/CS20256078
Published: 23 June 2025
.... Banales; Jose J.G. Marin; Joana Torres; Cecília M.P. Rodrigues Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease often associated with underlying inflammatory bowel disease (IBD). This study investigates how PSC predisposes individuals to altered inflammatory immune responses...
View article titled, Primary bile acid shapes peripheral immunity in inflammatory bowel disease-associated primary sclerosing cholangitis
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Includes: Supplementary data
Articles

Interleukin 34: a new modulator of human and experimental inflammatory bowel disease

Open Access
Stephanie Zwicker, Gisele L. Martinez, Madeleen Bosma, Marco Gerling, Reuben Clark, Mirjam Majster, Jan Söderman, Sven Almer, Elisabeth A. Boström
Journal: Clinical Science
Clin Sci (Lond) (2015) 129 (3): 281–290.
https://doi.org/10.1042/CS20150176
Published: 15 May 2015
...Stephanie Zwicker; Gisele L. Martinez; Madeleen Bosma; Marco Gerling; Reuben Clark; Mirjam Majster; Jan Söderman; Sven Almer; Elisabeth A. Boström IBD (inflammatory bowel disease), where CD (Crohn's disease) and UC (ulcerative colitis) represent the two main forms, are chronic inflammatory...
View article titled, Interleukin 34: a new modulator of human and experimental inflammatory bowel disease
Open the PDF for Interleukin 34: a new modulator of human and experimental inflammatory bowel disease in another window
Includes: Supplementary data