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Keywords: IDO
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Articles
Carolina Manganeli Polonio, Carla Longo de Freitas, Marília Garcia de Oliveira, Cristiano Rossato, Wesley Nogueira Brandão, Nágela Ghabdan Zanluqui, Lilian Gomes de Oliveira, Luiza Ayumi Nishiyama Mimura, Maysa Braga Barros Silva, Vera Lúcia Garcia Calich, Marcelo Gil Nisenbaum, Silvio Halpern, Lucila Evangelista, Mariangela Maluf, Paulo Perin, Carlos Eduardo Czeresnia, Jean Pierre Schatzmann Peron
Journal:
Clinical Science
Clin Sci (Lond) (2021) 135 (9): 1065–1082.
Published: 07 May 2021
... reduced CNS infiltrating cells, histopathology and demyelination. qPCR analysis evidenced the down-regulation of several pro-inflammatory genes and up-regulation of indoleamine-2,3-dioxygenase (IDO). Consistently, co-culturing of WT and IDO −/− meMSCs with T CD4 + cells evidenced the necessity of IDO...
