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Keywords: IFNγ
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Clin Sci (Lond) (2019) 133 (5): 645–663.
Published: 01 March 2019
... directly binds to the FOXM1 promoter to down-regulate its transcription. Interferon γ (IFNγ) promoted gemcitabine-induced cell apoptosis and inhibited cell proliferation in vitro and in vivo by FOXM1 inhibition. These data suggested that FOXM1 enhances chemoresistance to gemcitabine in pancreatic cancer...
Includes: Supplementary data