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The insecticide β-Cyfluthrin induces acute arrhythmic cardiotoxicity through interaction with NaV1.5 and ranolazine reverses the phenotype

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Maria Vitoria da Silva, Artur Santos-Miranda, Julliane V. Joviano-Santos, Diego Santos Souza, Leisiane Pereira Marques, Jaqueline Oliveira Sarmento, Samuel Santos Beserra, Danilo Roman-Campos
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (5): 329–343.
https://doi.org/10.1042/CS20211151
Published: 02 March 2022
... and Ranolazine ameliorated the phenotype. Understanding the insecticides’ impacts upon electromechanical properties of the heart is important for the development of therapeutic approaches to treat cases of pesticides intoxication. β-Cyfluthrin arrhythmias INa-L insecticide pyrethroid ranolazine...
View article titled, The insecticide β-Cyfluthrin induces acute arrhythmic cardiotoxicity through interaction with NaV1.5 and ranolazine reverses the phenotype
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Includes: Supplementary data