... © 2022 The Author(s). 2022 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Critical Illness Fasting Hypercortisolemia Ketogenesis Sepsis Tight...

..., infections or vital organ support. More gastrointestinal intolerance by energy-dense EN No difference in mortality Mechanistic studies have attributed the observed harm by providing early supplemental parenteral nutrition to feeding-induced suppression of autophagy and of ketogenesis...

..., but the sensitivity of lipolysis was impaired in patients with sepsis. In conclusion, sepsis impaired to a varying extent the action of insulin on endogenous glucose production, glucose utilization, lipolysis and ketogenesis. Whole-body glucose uptake was the most affected, with a total lack of response...

...Paulo R.L. De Vasconcelos; Michael G. W. Kettlewell; Dermot H. Williamson 1. The time course (12, 24 and 48 h) of changes in blood metabolites, and in gluconeogenesis and ketogenesis, in isolated hepatocytes from rats made septic by caecal ligation and puncture was measured. 2. Blood glucose...

... fatty acids and ketone bodies were lowered, particularly with hypertonic dialysis fluid. 5. The long-term effects of sustained hyper-insulinaemia, including suppression of lipolysis and ketogenesis, require further investigation. 26 1 1983 29 4 1983 © 1983 The Biochemical Society...

... precursors was significantly higher in the diabetic group at a given load. 4. The rate of ketogenesis was linearly related to the NEFA load in both groups; however, the rate of ketogenesis was twofold at a given load in the diabetic group. The highest rates of ketogenesis were found coincident...