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Keywords: Kidney
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Articles
Vidya K. Nagalakshmi, Jason P. Smith, Daisuke Matsuoka, Roberto Ariel Gomez, Maria Luisa Soledad Sequeira-Lopez
Journal:
Clinical Science
Clin Sci (Lond) (2024) 138 (23): 1527–1536.
Published: 29 November 2024
... 18 11 2024 19 11 2024 20 11 2024 © 2024 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2024 baroreceptor kidney Piezo2 renin Division of Intramural Research (DIR) 100017540 R01HL148044 Division of Diabetes...
Articles
Shobana Navaneethabalakrishnan, Bethany L. Goodlett, Hannah L. Smith, Robert A. Montalvo, II, Alyssa Cardenas, Brett M. Mitchell
Journal:
Clinical Science
Clin Sci (Lond) (2024) 138 (14): 921–940.
Published: 16 July 2024
... and functional impairment across multiple organs, including kidneys and gonads. However, it remains unclear whether promoting M2 macrophage polarization can alleviate the hypertension, inflammation, and end organ damage in mice with salt sensitive hypertension (SSHTN). Male and female mice were made hypertensive...
Includes: Supplementary data
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2024) 138 (11): 663–685.
Published: 31 May 2024
... scores are as accurate and precise as possible. MMDx provides insights on disease processes and highly reproducible results from a comparatively small amount of tissue and constitutes a general approach that is useful in many areas of medicine, including kidney, heart, lung, and liver transplants...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2023) 137 (18): 1477–1498.
Published: 22 September 2023
...Jun Pei; Xiaomao Tian; Chengjun Yu; Jin Luo; Yifan Hong; Jie Zhang; Sheng Wen; Yi Hua; Guanghui Wei Renal ischemia–reperfusion injuries (IRIs) are one of the leading causes of acute kidney injuries (AKIs). Selenium, as an essential trace element, is able to antioxidant stress and reduces...
Articles
Bethany L. Goodlett, Dakshnapriya Balasubbramanian, Shobana Navaneethabalakrishnan, Sydney E. Love, Emily M. Luera, Sunitha Konatham, Valorie L. Chiasson, Sophie Wedgeworth, Joseph M. Rutkowski, Brett M. Mitchell
Journal:
Clinical Science
Clin Sci (Lond) (2022) 136 (23): 1759–1772.
Published: 02 December 2022
... kidney-specific overexpression of VEGF-D (KidVD) experience renal lymphangiogenesis upon doxycycline administration. HTN was induced in KidVD+ and KidVD- mice by subcutaneous release of angiotensin II, administration of the nitric oxide synthase inhibitor L-NAME, or consumption of a 4% salt diet...
Includes: Supplementary data
Articles
Fuwei Zhang, Lifu Lei, Juan Huang, Weiwei Wang, Qian Su, Hongjia Yan, Caiyu Chen, Shuo Zheng, Hongmei Ren, Zhuxin Li, Pedro A. Jose, Yijie Hu, Liangyi Si, Chunyu Zeng, Jian Yang
Journal:
Clinical Science
Clin Sci (Lond) (2022) 136 (12): 989–1003.
Published: 29 June 2022
... or/and activity of G-protein-coupled receptor kinase 4 (GRK4) or genetic variants (e.g., GRK4γ142V) cause sodium retention and hypertension. Whether GRK4 plays a role in the regulation of AT 2 R in the kidney remains unknown. In the present study, we found that spontaneously hypertensive rats (SHRs) had increased...
Includes: Supplementary data
Articles
Riyaz Mohamed, Gene R. Crislip, Sarah McLarnon, Qingqing Wei, Paul M. O’Connor, Jennifer C. Sullivan
Journal:
Clinical Science
Clin Sci (Lond) (2022) 136 (11): 825–840.
Published: 01 June 2022
...Riyaz Mohamed; Gene R. Crislip; Sarah McLarnon; Qingqing Wei; Paul M. O’Connor; Jennifer C. Sullivan Acute kidney injury (AKI) due to ischemia is a serious and frequent clinical complication with mortality rates as high as 80%. Vascular congestion in the renal outer medulla occurs early after...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2021) 135 (22): 2575–2588.
Published: 26 November 2021
.... Treatment with tempol in paternal rats also reversed the increased expressions of AT 1 R and GRK4 in the kidney of their offspring. We suggest that paternal PM 2.5 exposure causes hypertension in offspring. The mechanism may be involved that paternal PM 2.5 exposure-associated oxidative stress induces...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2021) 135 (21): 2521–2540.
Published: 09 November 2021
...) and recessive (AR) forms of polycystic kidney disease (PKD). We provide here a basic overview of the origins and clinical aspects of ARPKD and ADPKD and discuss the implications of electrolyte transport in cystogenesis. Special attention is devoted to intracellular calcium handling by the cystic cells...
Articles
Ellen E. Gillis, Kasey Belanger, Mahmoud Abdelbary, Riyaz Mohamed, Jingping Sun, Michael W. Brands, Jennifer C. Sullivan
Journal:
Clinical Science
Clin Sci (Lond) (2021) 135 (19): 2329–2339.
Published: 13 October 2021
... 2 weeks, kidneys were harvested for flow cytometric analysis of T cells. Splenectomy increased BP in both sexes after 2 weeks. Renal Tregs decreased in both sexes after splenectomy, abolishing the sex differences in renal Tregs. In conclusion, splenic Tregs were comparable in male and female SHRs...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2021) 135 (17): 2165–2196.
Published: 17 September 2021
...Erika I. Boesen; Rahul M. Kakalij Hypertension is a major risk factor for cardiovascular disease, chronic kidney disease (CKD), and mortality. Troublingly, hypertension is highly prevalent in patients with autoimmune renal disease and hastens renal functional decline. Although progress has been...
Articles
Ana Paula Oliveira Leite, Xiao C. Li, Rumana Hassan, Xiaowen Zheng, Barbara Alexander, Dulce Elena Casarini, Jia L. Zhuo
Journal:
Clinical Science
Clin Sci (Lond) (2021) 135 (15): 1825–1843.
Published: 04 August 2021
...Ana Paula Oliveira Leite; Xiao C. Li; Rumana Hassan; Xiaowen Zheng; Barbara Alexander; Dulce Elena Casarini; Jia L. Zhuo In the present study, we tested the hypothesis that there are significant sex differences in angiotensin II (Ang II)-induced hypertension and kidney injury using male and female...
Articles
Gonzalo Ezequiel Pineda, Bárbara Rearte, María Florencia Todero, Andrea Cecilia Bruballa, Alan Mauro Bernal, Romina Jimena Fernandez-Brando, Martin Amadeo Isturiz, Elsa Zotta, Catalina Dirney Alba-Soto, Marina Sandra Palermo, María Victoria Ramos
Journal:
Clinical Science
Clin Sci (Lond) (2021) 135 (3): 575–588.
Published: 10 February 2021
... conclude that IL-10 absence has a protective role in an experimental model of HUS by reducing PMN recruitment into kidney and renal damage, and increasing mice survival. Correspondence: María Victoria Ramos ( [email protected] , [email protected] ) 16 04 2020 15 01 2021 26 01...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2020) 134 (22): 3023–3046.
Published: 24 November 2020
... [ 47–49 ]. Cardiovascular Developmental programming Heart Kidney Vasculature Correspondence: Stephane L. Bourque ( [email protected] ) 28 09 2020 07 11 2020 10 11 2020 © 2020 The Author(s). Published by Portland Press Limited on behalf of the Biochemical...
Articles
Yan Zhang, Shaoxiong Wang, Hefei Huang, Andi Zeng, Yu Han, Cindy Zeng, Shuo Zheng, Hongmei Ren, Yajing Wang, Yu Huang, Pedro A. Jose, Xin-Liang Ma, Chunyu Zeng, Ken Chen
Journal:
Clinical Science
Clin Sci (Lond) (2020) 134 (18): 2453–2467.
Published: 25 September 2020
... ) * These authors contributed equally to this work. 21 05 2020 15 09 2020 17 09 2020 17 09 2020 © 2020 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2020 adiponectin adipose tissue GRK4 hypertension kidney renal proximal tubule...
Includes: Supplementary data
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2020) 134 (13): 1751–1762.
Published: 10 July 2020
...Riyaz Mohamed; Olga Rafikova; Paul M. O’Connor; Jennifer C. Sullivan Renal ischemia is the most common cause of acute kidney injury. Damage-associated molecular patterns (DAMPs) initiate an inflammatory response and contribute to ischemia–reperfusion (IR) injury in males, yet the contribution...
Articles
Lucinda M. Hilliard Krause, Brandon A. Kemp, Amanda Suan Jui Tan, Emma S. Jones, Mark P. Del Borgo, Marie-Isabel Aguilar, Kate M. Denton, Robert M. Carey, Robert E. Widdop
Journal:
Clinical Science
Clin Sci (Lond) (2020) 134 (7): 871–884.
Published: 14 April 2020
... agreement with CAUL. Correspondence: Robert E. Widdop ( [email protected] ) or Robert M. Carey ( [email protected] ) angiotensin III AT2 receptor agonist kidney natriuresis vasodilation After the kidney sections had been spotted onto slides and washed with TBS...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2020) 134 (6): 641–656.
Published: 27 March 2020
... of type 2 diabetes, ischemic heart disease and hypertension. Several adverse factors converge and suppress the fetal renin–angiotensin–aldosterone system (RAAS). The aim of this review is to summarize data on the significance of RAAS for kidney development and adult hypertension. Genetic inactivation...
Articles
Jianyong Yin, Xuanchen Liu, Ting Zhao, Rulian Liang, Rui Wu, Fangfei Zhang, Yiwei Kong, Limei Liu, Tao Xing, Niansong Wang, Qing Zhao, Feng Wang
Journal:
Clinical Science
Clin Sci (Lond) (2020) 134 (1): 75–85.
Published: 17 January 2020
... was measured in human kidney biopsies with DN and in kidneys of db/db mice. The role of Renalase in the development of DN was examined using a genetically engineered mouse model: Renalase knockout mice with db/db background. The renoprotective effects of Renalase in DN was evaluated in db/db mice with Renalase...
Includes: Supplementary data
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2019) 133 (2): 167–180.
Published: 18 January 2019
...Mathilde L. Bonnemaison; Eileen S. Marks-Nelson; Erika I. Boesen Systemic lupus erythematosus (SLE) is an autoimmune disease predominantly affecting women and often leading to lupus nephritis and kidney damage. Endoplasmic reticulum (ER) stress has been implicated in several forms of kidney disease...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2019) 133 (1): 41–54.
Published: 03 January 2019
..., an interesting topic for study. The aim of the present review is to provide an extensive overview of the possible involvement of histamine in the onset and progression of DN. The evidence collected on the role of histamine in kidney function together with its well-known pleiotropic action suggest that this amine...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2018) 132 (17): 1977–1994.
Published: 14 September 2018
...Meg L. McFetridge; Mark P. Del Borgo; Marie-Isabel Aguilar; Sharon D. Ricardo Chronic kidney disease (CKD) is a major and growing public health concern with increasing incidence and prevalence worldwide. The therapeutic potential of stem cell therapy, including mesenchymal stem cells (MSCs...
Articles
Sarah C. Ray, Bansari Patel, Debra L. Irsik, Jingping Sun, Hiram Ocasio, Gene R. Crislip, Chunhua H. Jin, JianKang Chen, Babak Baban, Aaron J. Polichnowski, Paul M. O’Connor
Journal:
Clinical Science
Clin Sci (Lond) (2018) 132 (11): 1179–1197.
Published: 15 June 2018
...Sarah C. Ray; Bansari Patel; Debra L. Irsik; Jingping Sun; Hiram Ocasio; Gene R. Crislip; Chunhua H. Jin; JianKang Chen; Babak Baban; Aaron J. Polichnowski; Paul M. O’Connor Sodium bicarbonate (NaHCO 3 ) slows the decline in kidney function in patients with chronic kidney disease (CKD), yet...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2016) 130 (15): 1307–1326.
Published: 29 June 2016
... The Author(s). published by Portland Press Limited on behalf of the Biochemical Society 2016 AT2 receptor AT2R agonism cardiovascular compound 21 kidney The biological actions of the renin–angiotensin system (RAS) are regarded to be primarily mediated by the octapeptide, angiotensin II (Ang...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2014) 127 (7): 423–433.
Published: 17 June 2014
... nephropathy calcium-activated potassium channel inflammatory cell K Ca 3.1 kidney renal fibrosis Diabetic nephropathy is a major cause of ESKD (end-stage kidney disease) and premature mortality, affecting approximately 30% of patients with diabetes mellitus. Although strategies such as glycaemic...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2014) 127 (1): 15–17.
Published: 10 March 2014
... in the cardiovascular and renal system, its involvement in hypertensive organ dysfunctions, such as those that occur in kidney, has not been investigated. In the present issue of Clinical Science , Alique and co-workers have demonstrated that angiotensin II-induced renal inflammatory responses were attenuated in mice...
Articles
Matilde Alique, Esther Civantos, Elsa Sanchez-Lopez, Carolina Lavoz, Sandra Rayego-Mateos, Raquel Rodrigues-Díez, Ana Belén García-Redondo, Jesús Egido, Alberto Ortiz, Diego Rodríguez-Puyol, Manuel Rodríguez-Puyol, Marta Ruiz-Ortega
Journal:
Clinical Science
Clin Sci (Lond) (2014) 127 (1): 19–31.
Published: 10 March 2014
... blockers are renoprotective and down-regulate ILK in experimental kidney disease, but the involvement of ILK in the actions of AngII in the kidney has not been addressed. Therefore we have investigated whether ILK signalling modulates the kidney response to systemic AngII infusion in wild-type and ILK...
Includes: Supplementary data
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2014) 126 (10): 685–694.
Published: 27 January 2014
...Harshini Mudaliar; Carol Pollock; Usha Panchapakesan Diabetic nephropathy is the leading cause of kidney failure and its increasing prevalence and incidence has imposed global socio-economic stress on healthcare systems worldwide. Although historically considered a metabolic disorder, recent...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2014) 126 (5): 315–328.
Published: 25 October 2013
... factors and agents that control nephrin and Neph3 gene expression. glomerulus kidney KIRREL2 (kin of IRRE-like 2) nephrin NPHS1 (nephrosis 1, congenital, Finnish type) podocyte transcriptional regulation transcription factor The glomerulus is the filtering unit of the kidney...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2013) 124 (12): 701–710.
Published: 26 February 2013
... lines demonstrated similar elevations of BP (blood pressure) and plasma potassium after 4 weeks of TG induction. Withdrawal of doxycycline switched off mutant TG expression and the disappearance of the PHAII phenotype. Western blotting of microdissected kidney nephron segments confirmed that expression...
Includes: Supplementary data
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2013) 124 (6): 351–370.
Published: 27 November 2012
... by its action on a restricted number of tissues; however, it has now become clear that this hormone controls an array of cellular processes in many different tissues. The present review will focus on the role of insulin in the kidney in health and disease. Correspondence: Dr Richard Coward (email...
Articles
Mona Sedeek, Alex Gutsol, Augusto C. Montezano, Dylan Burger, Aurelie Nguyen Dinh Cat, Chris R. J. Kennedy, Kevin D. Burns, Mark E. Cooper, Karin Jandeleit-Dahm, Patrick Page, Cedric Szyndralewiez, Freddy Heitz, Richard L. Hebert, Rhian M. Touyz
Journal:
Clinical Science
Clin Sci (Lond) (2013) 124 (3): 191–202.
Published: 17 October 2012
... species) have been implicated in the development of diabetic nephropathy. Of the Nox isoforms in the kidney, Nox4 is important because of its renal abundance. In the present study, we tested the hypothesis that GKT136901, a Nox1/4 inhibitor, prevents the development of nephropathy in db / db (diabetic...
Includes: Supplementary data
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2012) 123 (6): 333–346.
Published: 29 May 2012
...Danielle Zimmerman; Kevin D. Burns Ang-(1–7) [angiotensin-(1–7)] is a biologically active heptapeptide component of the RAS (renin–angiotensin system), and is generated in the kidney at relatively high levels, via enzymatic pathways that include ACE2 (angiotensin-converting enzyme 2...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2012) 123 (1): 1–14.
Published: 12 March 2012
...Anke L. Lameris; Leo A. Monnens; René J. Bindels; Joost G. J. Hoenderop Magnesium (Mg 2+ ) balance is tightly regulated by the concerted actions of the intestine, bone and kidneys. This balance can be disturbed by a broad variety of drugs. Diuretics, modulators of the EGFR (epidermal growth factor...
Articles
Jan Neckář, Libor Kopkan, Zuzana Husková, František Kolář, František Papoušek, Herbert J. Kramer, Sung Hee Hwang, Bruce D. Hammock, John D. Imig, Jiří Malý, Ivan Netuka, Bohuslav Ošťádal, Luděk Červenka
Journal:
Clinical Science
Clin Sci (Lond) (2012) 122 (11): 513–527.
Published: 10 February 2012
... in this transgenic model of angiotensin II-dependent hypertension. angiotensin II epoxyeicosatrienoic acid hypertension kidney myocardial ischaemia/reperfusion injury soluble epoxide hydrolase inhibitor Ischaemic heart disease is the leading cause of mortality in industrialized nations [ 1...
Includes: Supplementary data
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2012) 122 (10): 439–447.
Published: 20 January 2012
... microRNA markers detectable in body fluids. We discuss the lessons learned and the experience gained from these studies. Several recent studies have begun to explore translational microRNA research in kidney disease and hypertension. Translational research of microRNAs in the kidney faces unique challenges...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2012) 122 (6): 281–288.
Published: 11 November 2011
... programming extracellular fluid hyperphagia kidney salt appetite Prenatal exposure to an adverse environment has a marked impact upon the developing kidney. People whose birthweights were towards the lower end of the normal range have fewer nephrons [ 1 ] and are at greater risk of developing...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2010) 118 (4): 269–279.
Published: 16 November 2009
...Elena Velkoska; Rachael G. Dean; Luke Burchill; Vicki Levidiotis; Louise M. Burrell Alterations within the RAS (renin–angiotensin system) are pivotal for the development of renal disease. ACE2 (angiotensin-converting enzyme 2) is expressed in the kidney and converts the vasoconstrictor AngII...
Articles
Paul R. Kalra, Jonathan R. Clague, Andrew J. Coats, Stefan D. Anker, Philip A. Poole-Wilson, Allan D. Struthers
Journal:
Clinical Science
Clin Sci (Lond) (2010) 118 (1): 71–77.
Published: 02 October 2009
...Paul R. Kalra; Jonathan R. Clague; Andrew J. Coats; Stefan D. Anker; Philip A. Poole-Wilson; Allan D. Struthers CNP (C-type natriuretic peptide) is a vasodilatory peptide produced by vascular endothelium and the human heart with a short half-life. CNP has been identified within the human kidney...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2010) 118 (1): 1–18.
Published: 28 September 2009
...Henrik Dimke; Joost G. Hoenderop; René J. Bindels The kidney plays an important role in maintaining the systemic Ca 2+ and Mg 2+ balance. Thus the renal reabsorptive capacity of these cations can be amended to adapt to disturbances in plasma Ca 2+ and Mg 2+ concentrations. The reabsorption of Ca 2...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2009) 117 (2): 75–84.
Published: 15 June 2009
... + . Western blotting and quantitative PCR showed that NKCC2 expression was increased, whereas NCC mRNA was not up-regulated. Na + /K + ATPase α 1 subunit expression did not differ from controls; however, there was a significant reduction in whole kidney pump activity (23.4±1.8 and 17.7±1.2 nmol...
Articles
Antonia Alcaraz, David Hernández, David Iyú, Rubén Mota, Noemí M. Atucha, Antonio J. Ortiz, Joaquín García-Estañ, María C. Ortiz
Journal:
Clinical Science
Clin Sci (Lond) (2008) 115 (2): 57–68.
Published: 12 June 2008
... (phenylephrine) and ACh (acetylcholine) in isolated perfused kidneys were measured. NO levels were calculated as 24-h urinary excretion of nitrites, ROS as TBARS (thiobarbituric acid-reacting substances), and peroxynitrite formation as the renal expression of nitrotyrosine. BDL rats had progressive sodium...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2008) 114 (9): 589–590.
Published: 02 April 2008
... 2008 glucagon glucose tolerance insulin deficiency kidney microalbuminuria Type 2 diabetes The existence of a second pancreatic hormone, one that raises plasma glucose concentrations, in addition to the glucose-lowering hormone insulin was deduced early in the 20th century and fully...
Articles
Long-term hyperglucagonaemia induces early metabolic and renal phenotypes of Type 2 diabetes in mice
Journal:
Clinical Science
Clin Sci (Lond) (2008) 114 (9): 591–601.
Published: 02 April 2008
... increased serum glucagon by 129% ( P <0.05), raised systolic BP (blood pressure) by 21 mmHg ( P <0.01), elevated fasting blood glucose by 42% ( P <0.01), impaired glucose tolerance ( P <0.01), increased the kidney weight/body weight ratio ( P <0.05) and 24 h urinary albumin excretion by 108...
Articles
Angela Schulz, Maria Schlesener, Judith Weiss, Jonna Hänsch, Norbert Wendt, Peter Kossmehl, Daniela Grimm, Roland Vetter, Reinhold Kreutz
Journal:
Clinical Science
Clin Sci (Lond) (2008) 114 (4): 305–311.
Published: 15 January 2008
... compared with SHRs ( P <0.0001). UAE was significantly higher in male (7-fold) compared with female MWF rats (162.6±15.9 compared with 24.0±5.5 mg/24 h respectively; P <0.0001), and only male MWF rats developed significant glomerulosclerosis and tubulointerstitial damage in the kidney ( P <0.0001...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2007) 113 (7): 297–311.
Published: 03 September 2007
... of the literature since Y2K (year 2000) is provided, with a general overview of PGs and their synthesis enzymes, and then specific considerations of each PG/prostanoid receptor system in the kidney. © The Authors Journal compilation © 2007 Biochemical Society 2007 More recent studies have also revealed...
Articles
Linda S. Pescatello, Bruce E. Blanchard, Gregory J. Tsongalis, Carl M. Maresh, Ann O'Connell, Paul D. Thompson
Journal:
Clinical Science
Clin Sci (Lond) (2007) 113 (5): 251–258.
Published: 01 August 2007
...' measurements at rest and during exercise [ 14 , 15 ] and greater reproducibility over office determinations [ 16 ]. © The Authors Journal compilation © 2007 Biochemical Society 2007 α-adducin blood pressure hypertension kidney physical activity polymorphism postexercise hypotension sodium...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2007) 112 (12): 583–597.
Published: 14 May 2007
... in the regulation of blood pressure, and the relationship between dopamine receptor subtypes and hypertension. In the kidney, D 1 receptor protein is expressed in the juxtaglomerular cell, proximal tubule, distal convoluted tubule, macula densa, cortical collecting duct and renal vasculature...
Articles
Antoinette Pechere-Bertschi, Gordana Sunaric-Megevand, Ivan Haefliger, Francesca Panarello, Marc Maillard, Michel Burnier
Journal:
Clinical Science
Clin Sci (Lond) (2007) 112 (6): 337–344.
Published: 12 February 2007
... 3 10 2006 The Biochemical Society 2007 arterial hypotension blood pressure circadian variation kidney normal pressure glaucoma orthostatic test sodium handling For several decades, COAG (chronic open angle glaucoma) has been considered as a disease essentially due...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2006) 111 (1): 21–34.
Published: 14 June 2006
... in the biological actions of the COX metabolites and receptor activation has made the net effect of COX inhibition on BP control in hypertension unpredictable. COX enzymes in the kidney vascular structures are responsible for the conversion of arachidonic acid into PG (prostaglandin) G/H 2 [ 2 , 3...
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