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Keywords: Kupffer cell
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Articles
Impact of PPAR-α induction on glucose homoeostasis in alcohol-fed mice
Available to PurchaseValérie Lebrun, Olivier Molendi-Coste, Nicolas Lanthier, Christine Sempoux, Patrice D. Cani, Nico van Rooijen, Peter Stärkel, Yves Horsmans, Isabelle A. Leclercq
Journal:
Clinical Science
Clin Sci (Lond) (2013) 125 (11): 501–511.
Published: 25 July 2013
... (peroxisome-proliferator-activated receptor-α) agonist Wy14,643 protected against OH-induced steatosis and KC (Kupffer cell) activation and almost abolished OH-induced insulin resistance. As KC activation may modulate insulin sensitivity, we repeated the clamp studies in mice depleted in KC to decipher...
Includes: Supplementary data
