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Keywords: LOX-1
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Articles

High-cholesterol diet during pregnancy induces maternal vascular dysfunction in mice: potential role for oxidized LDL-induced LOX-1 and AT 1 receptor activation

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Tamara Sáez, Floor Spaans, Raven Kirschenman, Tatsuya Sawamura, Sandra T. Davidge
Journal: Clinical Science
Clin Sci (Lond) (2020) 134 (17): 2295–2313.
https://doi.org/10.1042/CS20200764
Published: 04 September 2020
...Tamara Sáez; Floor Spaans; Raven Kirschenman; Tatsuya Sawamura; Sandra T. Davidge The lectin-like oxidized low-density-lipoprotein (oxLDL) receptor-1 (LOX-1) has been shown to induce angiotensin II (AngII) type 1 receptor (AT 1 ) activation, contributing to vascular dysfunction. Preeclampsia...
View articletitled, High-cholesterol diet during pregnancy induces maternal vascular dysfunction in mice: potential role for oxidized LDL-induced LOX-1 and AT 1 receptor activation
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Includes: Supplementary data
Articles

Alterations in vascular function by syncytiotrophoblast extracellular vesicles via lectin-like oxidized low-density lipoprotein receptor-1 in mouse uterine arteries

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Floor Spaans, Anita Quon, Stewart R. Rowe, Jude S. Morton, Raven Kirschenman, Tatsuya Sawamura, Dionne S. Tannetta, Ian L. Sargent, Sandra T. Davidge
Journal: Clinical Science
Clin Sci (Lond) (2018) 132 (21): 2369–2381.
https://doi.org/10.1042/CS20180639
Published: 13 November 2018
... function; however, the mechanism remains unknown. In rats, STBEVs were shown to reduce endothelium-mediated vasodilation via lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1), a multi-ligand scavenger receptor that has been associated with vascular dysfunction. Recently, LOX-1 was shown...
View articletitled, Alterations in vascular function by syncytiotrophoblast extracellular vesicles via lectin-like oxidized low-density lipoprotein receptor-1 in mouse uterine arteries
Open the PDF for Alterations in vascular function by syncytiotrophoblast extracellular vesicles via lectin-like oxidized low-density lipoprotein receptor-1 in mouse uterine arteries in another window