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Keywords: LPL S447X variant
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Philippa J. Talmud, David M. Flavell, Khaled Alfakih, Jackie A. Cooper, Anthony J. Balmforth, Mohan Sivananthan, Hugh E. Montgomery, Alistair S. Hall, Steve E. Humphries
Journal:
Clinical Science
Clin Sci (Lond) (2007) 112 (12): 617–624.
Published: 14 May 2007
...) LPL S447X variant LPL (lipoprotein lipase) is the key enzyme in plasma triacylglycerol (triglyceride) hydrolysis, liberating FAs for energy generation in the heart. LPL is highly expressed in adult heart [ 14 ], and is down-regulated in the hypertrophied heart of SHRs (spontaneously hypertensive...