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Keywords: Metastasis
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Clin Sci (Lond) (2022) 136 (18): 1367–1370.
Published: 26 September 2022
...Kai Jiang; Haiyan Chen; Kefeng Ding In the present commentary, we discuss new observations stating that angiopoietin-like protein 1 (ANGPTL1) attenuates cancer metastasis and stemness through Forkhead box O-3a (Foxo3a)–SRY-related HMG-box-2 (Sox2) axis in colorectal cancer ( Clin. Sci . (2022) 136...
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Clin Sci (Lond) (2022) 136 (11): 895–909.
Published: 06 June 2022
...Zhanzhan Li; Yanyan Li; Na Li; Liangfang Shen; Aibin Liu Changes to some Golgi subfamily member proteins are reported to be involved in tumor metastasis. However, the functional role and potential mechanism of the Golgi A8 family member B (GOLGA8B) in lung squamous cell carcinoma (LUSC) remains...
Includes: Supplementary data
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Clin Sci (Lond) (2020) 134 (4): 419–434.
Published: 27 February 2020
...He Liu; Yanlong Liu; Ping Sun; Kaiming Leng; Yi Xu; Liqi Mei; Peng Han; Bomiao Zhang; Kefei Yao; Chunbo Li; Junge Bai; Binbin Cui Cancer-derived exosomal miRNAs play an important role in the development of metastasis, but the effects and underlying mechanisms remain unclear. In the present study...
Includes: Supplementary data
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Clin Sci (Lond) (2019) 133 (19): 2019–2022.
Published: 11 October 2019
...Brittany Dewdney; Lionel Hebbard Hepatocellular carcinoma (HCC) remains one of the leading causes of cancer-related deaths around the globe. For patients receiving liver tumour resection, the risk of reoccurrence and metastasis is high. Cancer metastasis can occur as a consequence of a physical...
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Clin Sci (Lond) (2019) 133 (5): 681–695.
Published: 05 March 2019
... node metastasis. The expression levels of chemerin and Chemerin Receptor 23 (ChemR23) were positively correlated with the migration and invasion of OSCC cell lines. Recombinant chemerin (R-chemerin) enhanced the in vitro migration, invasion and proliferation of OSCC cells in a concentration-dependent...
Includes: Supplementary data
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Clin Sci (Lond) (2019) 133 (1): 83–99.
Published: 11 January 2019
..., cleavage of cell surface proteins, and subsequent release of soluble ectodomains promote cancer progression via induction of angiogenesis and metastasis. Moreover, there is increasing evidence for significance of a non-proteolytic function of ADAM8. With the disintegrin (DIS) domain ADAM8 binds integrins...
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Clin Sci (Lond) (2013) 124 (9): 567–579.
Published: 21 January 2013
... was conducted and pathoclinical data were extracted. Variables assessed included age at diagnosis, gender, date of diagnosis, date of surgery, date and type of chemotherapy, date of radiotherapy, TNM (tumour node metastasis) stage, relapse/metastasis status, date of relapse/metastasis, and date and vital status...
Includes: Supplementary data
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Clin Sci (Lond) (2004) 106 (4): 397–405.
Published: 01 April 2004
... gastric mucosa (6.93±0.58 versus 3.19±0.26, P <0.01) and showed a reverse correlation with apoptotic index in adenocarcinoma, but not in normal mucosa. In addition, abundance of c-FLIP was significantly associated with lymph node metastasis at both mRNA level ( P <0.05) and protein level ( P...