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1-5 of 5
Keywords: NLRP3
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Articles
Journal:
Clinical Science
Clin Sci (Lond) (2023) 137 (5): 333–351.
Published: 01 March 2023
... will focus on the role of NACHT, leucin-rich repeat and pyrin-containing protein 3 (NLRP3) inflammasome in the pathophysiology of sepsis. NLRP3 inflammasome is a multiproteic intracellular complex activated by infectious pathogens through a two-step process resulting in the release of the pro-inflammatory...
Articles
Bohao Liu, Zhong Wang, Ruyuan He, Rui Xiong, Guorui Li, Lin Zhang, Tinglv Fu, Chenyuan Li, Ning Li, Qing Geng
Journal:
Clinical Science
Clin Sci (Lond) (2022) 136 (4): 273–289.
Published: 21 February 2022
...Bohao Liu; Zhong Wang; Ruyuan He; Rui Xiong; Guorui Li; Lin Zhang; Tinglv Fu; Chenyuan Li; Ning Li; Qing Geng Background : NOD-like receptor family pyrin domain containing 3 (NLRP3)-mediated macrophage pyroptosis plays an important role in sepsis-induced acute lung injury (ALI). Inhibition...
Includes: Supplementary data
Articles
Mariana Rodrigues Davanso, Amanda Rabello Crisma, Tárcio Teodoro Braga, Laureane Nunes Masi, Cátia Lira do Amaral, Vinícius Nunes Cordeiro Leal, Dhêmerson Souza de Lima, Thiago Andrade Patente, José Alexandre Barbuto, Maria L. Corrêa-Giannella, Mario Lauterbach, Carl Christian Kolbe, Eicke Latz, Niels Olsen Saraiva Camara, Alessandra Pontillo, Rui Curi
Journal:
Clinical Science
Clin Sci (Lond) (2021) 135 (1): 19–34.
Published: 05 January 2021
...; Niels Olsen Saraiva Camara; Alessandra Pontillo; Rui Curi Type 1 diabetes mellitus (T1D) is a chronic autoimmune disease characterized by insulin-producing pancreatic β-cell destruction and hyperglycemia. While monocytes and NOD-like receptor family-pyrin domain containing 3 (NLRP3) are associated...
Includes: Supplementary data
Articles
Danlin Liu, Gavin Richardson, Fehmi M. Benli, Catherine Park, João V. de Souza, Agnieszka K. Bronowska, Ioakim Spyridopoulos
Journal:
Clinical Science
Clin Sci (Lond) (2020) 134 (17): 2243–2262.
Published: 03 September 2020
.... The SASP is characterised by the release of inflammatory cytokines, elevated activation of the NLRP3 inflammasome, altered regulation of acetylcholine (ACh) nicotinic receptors, and abnormal NAD + metabolism. Therefore, SASP may be ‘druggable’ by small molecule therapeutics targeting those emerging...
Articles
Tárcio Teodoro Braga, Wesley Nogueira Brandao, Hatylas Azevedo, Fernanda Fernandes Terra, Amanda Campelo L. Melo, Felipe Valença Pereira, Vinicius Andrade-Oliveira, Meire Ioshie Hiyane, Jean Pierre S. Peron, Niels Olsen Saraiva Camara
Journal:
Clinical Science
Clin Sci (Lond) (2019) 133 (17): 1901–1916.
Published: 13 September 2019
...Tárcio Teodoro Braga; Wesley Nogueira Brandao; Hatylas Azevedo; Fernanda Fernandes Terra; Amanda Campelo L. Melo; Felipe Valença Pereira; Vinicius Andrade-Oliveira; Meire Ioshie Hiyane; Jean Pierre S. Peron; Niels Olsen Saraiva Camara NLRP3 inflammasome [NLR (nucleotide-binding domain, leucine-rich...
Includes: Supplementary data
