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Keywords: Palmitic acid
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Articles
Journal:
Clinical Science
Clin Sci (Lond) (2019) 133 (1): 101–116.
Published: 11 January 2019
... GPR120 and β-cell function, its agonists docosahexaenoic acid (DHA) and GSK137647A were used in palmitic acid (PA)-induced pancreatic β-cell dysfunction, coupled with GPR120 knockdown (KD) in MIN6 cells and GPR120 knockout (KO) mice to identify the underlying signaling pathways. In vitro and ex vivo...
Includes: Supplementary data
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2011) 120 (5): 179–181.
Published: 19 November 2010
.... Correspondence: Dr Henrik Ortsäter (email [email protected] ). 25 10 2010 2 11 2010 2 11 2010 2 11 2010 © The Authors Journal compilation © 2011 Biochemical Society 2011 arachidonic acid lipotoxicity palmitic acid pancreatic β-cell reactive oxygen species...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2011) 120 (5): 195–206.
Published: 19 November 2010
... fatty acids such as PA (palmitic acid) are detrimental to β-cell function compared with unsaturated fatty acids. In the present study, we describe the effect of the polyunsaturated AA (arachidonic acid) on the function of the clonal pancreatic β-cell line BRIN-BD11 and demonstrate AA-dependent...