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Keywords: Paneth cell
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Articles
Chronic GPER activation prompted the proliferation of ileal stem cell in ovariectomized mice depending on Paneth cell–derived Wnt3
Available to PurchaseJianbo Liu, Kaixuan Liu, Shiquan Chai, Runze Xu, Ying Wang, Yundi Zhang, Shuanglian Wang, Chuanyong Liu, Bing Xue
Journal:
Clinical Science
Clin Sci (Lond) (2023) 137 (1): 109–127.
Published: 05 January 2023
... and cyclin B1 in organoids. After G-1 treatment in vivo or in vitro , Paneth cell–derived Wnt3, Wnt3 effector β-catenin and Wnt target genes c-Myc and Cyclin D1 increased in ileum or organoids. Once blocking the secretion of Wnt3 from Paneth cells, the effects of G-1 on organoids growth, ISCs marker genes...
Includes: Supplementary data
