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1-7 of 7
Keywords: S-adenosylmethionine
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Articles
Manon V. Van Hecke, Jacqueline M. Dekker, Giel Nijpels, Tom Teerlink, Cornelis Jakobs, Ronald P. Stolk, Rob J. Heine, Lex M. Bouter, Bettine C.P. Polak, Coen D.A. Stehouwer
Journal:
Clinical Science
Clin Sci (Lond) (2008) 114 (7): 479–487.
Published: 29 February 2008
... and retinal microvascular disorders in subjects with and without Type 2 diabetes. In this population-based study of 256 participants, aged 60–85 years, we determined total plasma homocysteine, SAM ( S -adenosylmethionine) and SAH ( S -adenosylhomocysteine) in plasma and erythrocytes, total folate in serum...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2005) 108 (5): 449–456.
Published: 22 April 2005
.... homocysteine, AdoMet ( S -adenosylmethionine), AdoHcy ( S -adenosylhomocysteine), serine and glycine. Primed, continuous infusions with [ 2 H 3 -methyl-1- 13 C]methionine were used to determine flux rates of methionine transmethylation, homocysteine remethylation and homocysteine trans-sulphuration. Metabolic...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1998) 94 (6): 677–685.
Published: 01 June 1998
... S -adenosylhomocysteine S -adenosylmethionine brain protein carboxymethylation protein methyltransferase Clinical Science (1998) 94.677465 (Printed in Great Britain) Regional differences in protein carboxymethylation in post-mortem human brain Michael GOGGINS, John M. SCOTT and Donald G...
Articles
Franziska M. T. Loehrer, Walter E. Haefeli, Christian P. Angst, Garry Browne, Greta Frick, Brian Fowler
Journal:
Clinical Science
Clin Sci (Lond) (1996) 91 (1): 79–86.
Published: 01 July 1996
... of homocysteine to methionine), S-adenosylmethionine (the first metabolite of methionine) and S-adenosylhomocysteine (the demethylated product of S-adenosylmethionine) over 24 h in 12 healthy subjects. 3. As well as the expected increase in homocysteine (from 8.0 ± 1.3 to 32.6 ± 10.3 μmol/l, mean ± SD, P...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1995) 88 (4): 471–477.
Published: 01 April 1995
...M. McKeever; A. Molloy; P. Young; S. Kennedy; D. G. Kennedy; J. M. Scott; D. G. Weir 1. Pigs treated with nitrous oxide for periods of 1, 2 and 4 months demonstrated markedly reduced levels of methionine synthase and concomitant reduction in the ratio of S -adenosylmethionine to S...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1995) 88 (1): 73–79.
Published: 01 January 1995
...M. McKeever; A. Molloy; D. G. Weir; P. B. Young; D. G. Kennedy; S. Kennedy; J. M. Scott 1. The ratio of the methyl donor, S -adenosylmethionine, to the co-product, S -adenosylhomocysteine (the methylation ratio) is known to control the activity of methyltransferases in tissues. Inactivation...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1994) 86 (6): 697–702.
Published: 01 June 1994
... is that this is mediated by deficiency of the methyl-donor S -adenosylmethionine. 2. To test this in humans, we have measured cerebrospinal fluid concentrations of 5-hydroxyindoleacetic acid and homovanillic acid, metabolites of 5-hydroxytryptamine and dopamine, respectively, in children with inborn errors of the methyl...