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Keywords: SA 446
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Complex Competitive and Non-Competitive Inhibition of Rat Lung Angiotensin-Converting Enzyme by Inhibitors Containing Thiol Groups: Captopril and SA 446
Available to Purchase
Journal:
Clinical Science
Clin Sci (Lond) (1981) 61 (s7): 277s–280s.
Published: 01 December 1981
.... Teprotide was the least potent inhibitor with a K 1 of near 20 nmol/l whereas captopril (SQ 14 225) and SA 446 were both approximately 10 times and MK 421 approximately 20 times more potent. 5. Two inhibitors which lacked thiol groups [teprotide or SQ 20 881 and N -(1- S -1-carboxy-3-phenylpropyl)- l -Ala...