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Keywords: SCH 42495
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Journal:
Clinical Science
Clin Sci (Lond) (1997) 93 (1): 43–50.
Published: 01 July 1997
...-labelled RB104. 2. SCH 42354, the active di-acid of the ethylester prodrug, SCH 42495, caused a concentration-dependent displacement of 125 I-labelled RB104 from rat renal NEP. The concentration of SCH 42354 that displaced 50% of radioligand bound to the enzyme NEP (IC 50 ) was 3.3 ± 0.1 nmol/1 (mean ± SEM...