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Journal: Clinical Science
Clin Sci (Lond) (2018) 132 (13): 1403–1415.
Published: 09 July 2018
...Yun Zhang; Xiao-Ming Meng; Xiao-Ru Huang; Hui Yao Lan It is well established that Smad3 is a key downstream effector of transforming growth factor-β (TGF-β) signaling in tissue fibrogenesis. We reported here that targetting Smad3 specifically with a Smad3 inhibitor SIS3 is able to prevent or halt...