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Keywords: STAT1
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Clin Sci (Lond) (2023) 137 (5): 367–383.
Published: 09 March 2023
... that LPS-induced Stat1 Ser727 phosphorylation promotes Irf1 transactivation, resulting in downstream up-regulation of Lif that inhibits endothelial cell proliferation. Conclusions: These results demonstrate the existence of a p-Stat1 Ser727 -Irf1-Lif axis that inhibits lung endothelial cell regeneration...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2019) 133 (5): 645–663.
Published: 01 March 2019
.... IFNγ could be used to down-regulate the expression of FOXM1 through STAT1 phosphorylation, thereby increasing the sensitivity of pancreatic cancer cells to gemcitabine. These studies suggested the sensitization by IFNγ in pancreatic ductal adenocarcinoma (PDAC) chemotherapy, which requires further...
Includes: Supplementary data