... by Portland Press Limited on behalf of the Biochemical Society 2023 Cancer Critical Care Gut Intensive Care Sepsis T cell Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection [ 1 ]. The inciting infectious agent can be bacterial, viral...

... and in vitro mixed culture system. Microglia overexpressing CD200R produced less inflammatory chemokines and reduced the loss of TH + neurons. In addition, HMGB1 A box decreased the level of CCL5 and significantly inhibited the infiltration of almost all T cells including Th17 and the proportion of Th17 in CD4...

... receptor 4 (TLR4)]. Cells of the innate immune system possess powerful killing mechanisms, e.g. the phagocyte NADPH oxidase in granulocytes and macrophages. © The Authors Journal compilation © 2015 Biochemical Society 2015 NADPH oxidase 2 autoimmune disease B cell T cell...