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Keywords: Tauroursodeoxycholic acid
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Potential therapeutic action of tauroursodeoxycholic acid against cholestatic liver injury via hepatic Fxr/Nrf2 and CHOP-DR5-caspase-8 pathway

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New discoveries in bile acids, gut microbiota and host interactions in health and diseases
Guochao Song, Fengyi Weng, Bin Zou, Jing Zhao, Jingyi Jin, Dongming Yan, Kai Huang, Xin Sun, Chenghai Liu, Yiyang Hu, Yue Li, Furong Qiu
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (7): 561–577.
https://doi.org/10.1042/CS20220674
Published: 13 April 2023
...Guochao Song; Fengyi Weng; Bin Zou; Jing Zhao; Jingyi Jin; Dongming Yan; Kai Huang; Xin Sun; Chenghai Liu; Yiyang Hu; Yue Li; Furong Qiu Cholestasis is a pathophysiologic syndrome with limited therapeutic options. Tauroursodeoxycholic acid (TUDCA) has been employed to treat hepatobiliary disorders...
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Includes: Supplementary data