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Keywords: Transgenic rats
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Daniele T. Alves, Luiz Felipe Mendes, Walkyria O. Sampaio, Leda M.C. Coimbra-Campos, Maria Aparecida R. Vieira, Anderson J. Ferreira, Almir S. Martins, Elena Popova, Mihail Todiras, Fatimunnisa Qadri, Natalia Alenina, Michael Bader, Robson A.S. Santos, Maria Jose Campagnole-Santos
Journal:
Clinical Science
Clin Sci (Lond) (2021) 135 (18): 2197–2216.
Published: 21 September 2021
... of the angiotensin (Ang)-converting enzyme (ACE) 2/Ang-(1-7)/MAS receptor pathway of the renin–angiotensin system (RAS) induces protective mechanisms in different diseases. Herein, we describe the cardiovascular phenotype of a new transgenic rat line (TG7371) that expresses an Ang-(1-7)-producing fusion protein...
Includes: Supplementary data