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Keywords: Tryptophan metabolism
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Articles
Flavonoid derivative DMXAA attenuates cisplatin-induced acute kidney injury independent of STING signaling
Available to PurchaseLingling Lu, Weihua Liu, Shumin Li, Mi Bai, Yu Zhou, Zhaohui Jiang, Zhanjun Jia, Songming Huang, Aihua Zhang, Wei Gong
Journal:
Clinical Science
Clin Sci (Lond) (2023) 137 (6): 435–452.
Published: 21 March 2023
... in kidneys of AKI mice, especially regulated the tryptophan metabolism. Collectively, therapeutic administration of DMXAA ameliorates cisplatin-induced AKI independent of STING, suggesting a promising potential for preventing nephrotoxicity induced by cisplatin-based chemotherapy. Acute kidney injury...
Includes: Supplementary data