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Keywords: Tumor Microenvironment
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Articles
Clin Sci (Lond) (2024) 138 (11): 617–634.
Published: 24 May 2024
...Philipp F. Arndt; Kati Turkowski; Michael J. Cekay; Bastian Eul; Friedrich Grimminger; Rajkumar Savai The tumor microenvironment (TME) plays a central role in the development of cancer. Within this complex milieu, the endothelin (ET) system plays a key role by triggering epithelial-to-mesenchymal...
Articles
Clin Sci (Lond) (2021) 135 (10): 1289–1293.
Published: 28 May 2021
...Gregor Werba; Tamas A. Gonda Pancreatic ductal adenocarcinoma (PDAC) features a hostile tumor microenvironment (TME) that renders it remarkably resistant to most therapeutic interventions. Consequently, survival remains among the poorest compared with other gastrointestinal cancers. Concerted...
Articles
Clin Sci (Lond) (2019) 133 (1): 83–99.
Published: 11 January 2019
... Tumor Microenvironment A disintegrin and metalloproteinase (ADAM) 8 (ADAM8) is a type I transmembrane (TM) glycoprotein consisting of an N -terminal prodomain, followed by a metalloproteinase-, disintegrin (DIS)-, cysteine-rich-, epidermal growth factor (EGF)-like- and TM domain...