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Keywords: Twist
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Articles
Melatonin suppresses lung cancer metastasis by inhibition of epithelial–mesenchymal transition through targeting to Twist
Available to PurchaseChia-Chia Chao, Po-Chun Chen, Pei-Chen Chiou, Chin-Jung Hsu, Po-I Liu, Yi-Chen Yang, Russel J. Reiter, Shun-Fa Yang, Chih-Hsin Tang
Journal:
Clinical Science
Clin Sci (Lond) (2019) 133 (5): 709–722.
Published: 15 March 2019
... that melatonin down-regulated EMT by inhibiting Twist/Twist1 (twist family bHLH transcription factor 1) expression. This effect was mediated by MT1 receptor, PLC, p38/ERK and β-catenin signaling cascades. Twist expression was positively correlated with tumor stage and negatively correlated with MT1 expression...
