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Keywords: Type II diabetes
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Articles
Clin Sci (Lond) (2006) 111 (2): 119–126.
Published: 13 July 2006
... under identical nutritional and physical activity conditions in patients with Type II diabetes and healthy normoglycaemic controls. A total of 11 male patients with Type II diabetes and 11 healthy matched controls participated in a 24 h CGMS (continuous subcutaneous glucose-monitoring system) assessment...
Articles
Clin Sci (Lond) (2006) 111 (2): 127–134.
Published: 13 July 2006
...Fredrik Sjöstrand; Thomas Nyström; Robert G. Hahn Physicians are often unclear about how fast intravenous glucose solutions should be administered to adequately hydrate patients with Type II diabetes while avoiding hyperglycaemia and excessive plasma volume expansion. The aim of the present study...
Articles
Clin Sci (Lond) (2006) 111 (1): 53–59.
Published: 14 June 2006
...Niels H. Andersen; Steen H. Poulsen; Per L. Poulsen; Søren T. Knudsen; Kjeld Helleberg; Klavs W. Hansen; Dines S. Dinesen; Hans Eiskjær; Allan Flyvbjerg; Carl E. Mogensen Decreased left ventricular long-axis function may be the earliest stage in subclinical heart failure in Type II diabetes...
Articles
Clin Sci (Lond) (2006) 110 (6): 673–681.
Published: 15 May 2006
...Thomas Nyström; Arne Nygren; Åke Sjöholm The pathophysiology of insulin resistance and atherosclerosis may share a common inflammatory basis, maintaining endothelial dysfunction, suggesting why patients with T2DM (Type II diabetes mellitus) have an impaired prognosis after an MI (myocardial...
Articles
Clin Sci (Lond) (2006) 110 (4): 467–473.
Published: 15 March 2006
... the relationship between [Hb] and FMD (flow-mediated vasodilation; 5 min of cuff ischaemia) of the radial and brachial arteries in 33 normal subjects and in 13 patients with Type II diabetes, known to have impaired NO-mediated vasodilation. The smaller radial artery provided the more sensitive test, as it had a 2...
Articles
Clin Sci (Lond) (2006) 110 (4): 409–425.
Published: 15 March 2006
... data suggest that high levels of physical activity or fitness may be particularly beneficial to individuals with insulin-resistant conditions, such as the metabolic syndrome, Type II diabetes or obesity. These individuals, if unfit and sedentary, exhibit increased CVD risk, but their dose–response...
Articles
Clin Sci (Lond) (2005) 109 (3): 243–256.
Published: 24 August 2005
...Christine M. Kusminski; Philip G. Mcternan; Sudhesh Kumar Resistin is a member of a class of cysteine-rich proteins collectively termed resistin-like molecules. Resistin has been implicated in the pathogenesis of obesity-mediated insulin resistance and T2DM (Type II diabetes mellitus), at least...
Articles
Clin Sci (Lond) (2005) 109 (3): 297–302.
Published: 24 August 2005
...) and chylomicrons] determined by a novel HPLC method, with adiponectin, which is decreased in Type II diabetes and assumed to be involved in dysregulated metabolism and atherogenesis. Type II diabetic patients who were not treated with insulin, statins and fibrates were enrolled. Study subjects included Type II...
Articles
Clin Sci (Lond) (2005) 109 (2): 189–197.
Published: 25 July 2005
...-sectional study of 58 Type II diabetic subjects and 50 controls, we examined the fasting plasma LDL basal conjugated diene concentration [a direct measurement of circulating oxLDL (oxidatively modified LDL)], lipoprotein particle size by NMR spectroscopy, PON-1 polymorphisms (coding region polymorphisms...
Articles
Clin Sci (Lond) (2005) 108 (6): 507–513.
Published: 24 May 2005
... with Type II diabetes. Patients with Type II diabetes were treated with 1 g of ascorbic acid three times a day for 2 weeks in a randomized placebo-controlled double-blind cross-over design. Microvascular reactivity was assessed by vital capillaroscopy and PRH (post-occlusive reactive hyperaemia). hs-CRP...
Articles
Clin Sci (Lond) (2005) 108 (2): 121–128.
Published: 21 January 2005
...Thomas NYSTRÖM; Arne NYGREN; Åke SJÖHOLM The atherosclerotic process is an ongoing dynamic and progressive state arising from endothelial dysfunction and inflammation. Although suffering from an acute coronary artery disease, patients with Type II diabetes have a poor outcome compared with non...
Articles
Clin Sci (Lond) (2004) 107 (5): 485–495.
Published: 26 October 2004
...Harald MISCHAK; Thorsten KAISER; Michael WALDEN; Meike HILLMANN; Stefan WITTKE; Alena HERRMANN; Stefan KNUEPPEL; Hermann HALLER; Danilo FLISER Renal disease in patients with Type II diabetes is the leading cause of terminal renal failure and a major healthcare problem. Hence early identification...
Articles
Clin Sci (Lond) (2004) 106 (2): 141–145.
Published: 01 February 2004
...Susan E. OZANNE; Rohan LEWIS; Bridget J. JENNINGS; C. Nicholas HALES Poor early growth is associated with Type II diabetes, hypertension and other features of the metabolic syndrome in adulthood. It has been suggested that this results from the development of a thrifty phenotype by a malnourished...
Articles
Clin Sci (Lond) (2003) 105 (5): 531–532.
Published: 01 November 2003
... sensitivity minimal model Type II diabetes Clinical Science (2003) 105, 531 532 (Printed in Great Britain) 531 C O M M E N T The minimal model: an evolving methodology A B S T R A C T After more than 20 years, minimal model analysis of intravenous glucose tolerance test glucose and insulin concentrations...
Articles
Clin Sci (Lond) (2003) 105 (5): 551–560.
Published: 01 November 2003
... ( S G ) with the minimal model of glucose kinetics using data collected during insulin-modified intravenous glucose tolerance test (IVGTT) and made comparison with the standard non-linear regression analysis. After fasting overnight, subjects with newly presenting Type II diabetes according to World...
Articles
Clin Sci (Lond) (2003) 104 (3): 211–215.
Published: 28 January 2003
...Natalia L. DUARTE; Stephen COLAGIURI; Taniela PALU; Xing L. WANG; David E.L. WILCKEN As there is a high prevalence of obesity in Tonga, we aimed to determine the distribution of the β2 adrenoceptor gene Gln 27 Glu polymorphism and to assess its relevance to obesity and to Type II diabetes, known...
Articles
Clin Sci (Lond) (2002) 103 (6): 559–566.
Published: 30 October 2002
...L.B. BORGHOUTS; A.J.M. WAGENMAKERS; P.L.L. GOYENS; H.A. KEIZER Recently, we observed that impairments exist in skeletal muscle free fatty acid (FFA) utilization during exercise in obese subjects with Type II diabetes. The main objective of the present study was to investigate whether plasma FFA...
Articles
Clin Sci (Lond) (2002) 103 (4): 397–402.
Published: 05 September 2002
... to the pressure effect of noradrenaline. Moreover, this variant also influences blood triacylglycerol levels and, to a degree, glucose metabolism. metabolic syndrome noradrenaline triacylglycerol Type II diabetes Correspondence : Dr Giancarlo Tonolo (e-mail giantono2001@yahoo.it ). 4 3 2002...
Articles
Clin Sci (Lond) (2002) 102 (2): 151–166.
Published: 03 January 2002
... insulin resistance oestrogens polycystic ovarian syndrome Type II diabetes 151Clinical Science (2002) 102, 151 166 (Printed in Great Britain) + R E V I E W Sex steroids and insulin resistance Callum LIVINGSTONE* and Mary COLLISON *Centre for Clinical Science and Measurement, School of Biomedical...
Articles
Clin Sci (Lond) (2001) 101 (3): 235–241.
Published: 03 August 2001
...Michael J. SAMPSON; Sian ASTLEY; Tristan RICHARDSON; Gavin WILLIS; Isabel R. DAVIES; David A. HUGHES; Sue SOUTHON In vivo supplementation studies of the antioxidant α-tocopherol in human Type II diabetes have used surrogate, rather than direct, markers of oxidative damage/antioxidant protection...
Articles
Clin Sci (Lond) (2000) 98 (6): 673–680.
Published: 10 May 2000
...P. A. SENIOR; T. H. THOMAS; S. M. MARSHALL In essential hypertension and diabetic nephropathy, sodium–lithium countertransport (Na–Li CT) is an inherited marker, subject to metabolic influences, of cardiovascular risk. Studies in Type II diabetes, taking clinical phenotypes as their starting point...
Articles
Clin Sci (Lond) (1999) 97 (4): 421–428.
Published: 24 August 1999
... lipolysis, in obesity-associated type II diabetes during overnight-fasted conditions (baseline) and during intravenous infusion of the non-selective β-agonist isoprenaline. Basal subcutaneous adipose tissue blood flow and isoprenaline-induced increases in adipose tissue blood flow were not signifcantly...