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Keywords: Wnt/β-catenin signaling
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Articles

Chronic GPER activation prompted the proliferation of ileal stem cell in ovariectomized mice depending on Paneth cell–derived Wnt3

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Jianbo Liu, Kaixuan Liu, Shiquan Chai, Runze Xu, Ying Wang, Yundi Zhang, Shuanglian Wang, Chuanyong Liu, Bing Xue
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (1): 109–127.
https://doi.org/10.1042/CS20220392
Published: 05 January 2023
... and Wnt/β-catenin signaling were abolished. G-1 did not affect the number of Paneth cells in ex vivo organoids, while activated Mmp7/cryptdin program in Paneth cells, promoted their maturation, and increased the expression of lysozyme protein. G-1 pretreatment in OVX mice inhibited radiation-induced ISCs...
View articletitled, Chronic GPER activation prompted the proliferation of ileal stem cell in ovariectomized mice depending on Paneth cell–derived Wnt3
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Includes: Supplementary data
Articles

HEG1 indicates poor prognosis and promotes hepatocellular carcinoma invasion, metastasis, and EMT by activating Wnt/β-catenin signaling

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Yan-rong Zhao, Ji-long Wang, Cong Xu, Yi-ming Li, Bo Sun, Lian-yue Yang
Journal: Clinical Science
Clin Sci (Lond) (2019) 133 (14): 1645–1662.
https://doi.org/10.1042/CS20190225
Published: 25 July 2019
... invasion, metastasis and EMT by activating Wnt/β-catenin signaling; and can serve as a potentially valuable prognostic biomarker and therapeutic target for HCC. Correspondence: Lian-yue Yang ( [email protected] ) HEG1 hepatocellular carcinoma prognosis metastasis epithelial-mesenchymal...
View articletitled, HEG1 indicates poor prognosis and promotes hepatocellular carcinoma invasion, metastasis, and EMT by activating Wnt/β-catenin signaling
Open the PDF for HEG1 indicates poor prognosis and promotes hepatocellular carcinoma invasion, metastasis, and EMT by activating Wnt/β-catenin signaling in another window
Includes: Supplementary data