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Keywords: acid hydrolase
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Acid Hydrolase Activities and Lysosomal Integrity in Liver Biopsies from Patients with Iron Overload
Journal:
Clinical Science
Clin Sci Mol Med (1976) 50 (1): 75–78.
Published: 01 January 1976
... was essentially normal in biopsies from patients with a wide variety of chronic liver diseases. 5. It is suggested that iron accumulation damages the lysosomal membrane, releasing acid hydrolases into the cytoplasm and thus initiating cell damage. 20 9 1975 © 1976 The Biochemical Society...