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Keywords: adenosine
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Clin Sci (Lond) (2004) 107 (5): 467–475.
Published: 26 October 2004
... receptor blockade). To avoid vasoconstrictor effects induced by ET A receptor stimulation, additional experiments were performed in the presence of the vasodilator adenosine (2.0 mg·kg −1 of body weight·min −1 ). Myocardial function was also examined during aortic clamping so as to circumvent the effect...
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Clin Sci (Lond) (2004) 106 (1): 75–82.
Published: 01 January 2004
...Henri J. L. M. TIMMERS; Gerard A. RONGEN; John M. KAREMAKER; Wouter WIELING; Henri A. M. MARRES; Jacques W. M. LENDERS The direct vasodilatory and negative chronotropic effects of adenosine in humans are counterbalanced by a reflex increase in sympathetic nerve traffic. A suggested mechanism...
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Clin Sci (Lond) (2000) 98 (3): 303–311.
Published: 09 February 2000
... examined the role of adenosine in mediating these effects using the isolated perfused rat kidney. Kidneys were perfused with a 6.7%-(w/v)-albumin-based perfusate supplemented with glucose and amino acids ( n = 6 per group). They were exposed to diatrizoate [20 mg of iodine (mgI)/ml; osmolality 1650 mOsm/kg...
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Clin Sci (Lond) (1999) 96 (6): 597–604.
Published: 07 May 1999
...Gerard A. RONGEN; Steven C. BROOKS; Michael J. POLLARD; Shin-ichi ANDO; Hilmi R. DAJANI; Catherine F. NOTARIUS; John S. FLORAS By stimulating afferent nerve endings in skeletal muscle, heart, kidney and the carotid body, adenosine infusion evokes a receptor-specific sympatho-excitatory reflex...
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Clin Sci (Lond) (1999) 96 (4): 349–355.
Published: 01 April 1999
...P. FORSYTHE; L. P. A. MCGARVEY; L. G. HEANEY; J. MACMAHON; M. ENNIS Previous studies have shown that in vitro adenosine enhances histamine release from activated human lung mast cells obtained by enzymic dispersion of lung parenchyma. However, adenosine alone has no effect on histamine release from...
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Clin Sci (Lond) (1995) 89 (3): 227–232.
Published: 01 September 1995
...Samuel S. Lee; Jung-Min Pak; Shaun M. Medlicott; Arieh Bomzon 1. There is currently considerable interest in the role of locally produced vasodilators such as nitric oxide and adenosine in the pathogenesis of the peripheral vasodilatation of cirrhosis. However, the signal transduction pathways...
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Clin Sci (Lond) (1992) 83 (5): 511–518.
Published: 01 November 1992
... of myocytes which might have regained normal function, or does reperfusion merely hasten Key words adenosine, adhesion molecules, complement, endothelium, inflammation, leukotrienes, myocardial ischaemia, neutrophils, oxygen free radicals, reperfusion injury. Abbreviations: ICAM-I, intercellular adhesion...
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Clin Sci (Lond) (1991) 80 (2): 107–112.
Published: 01 February 1991
...S. T. Parsons; T. L. Griffiths; J. M. L. Christie; S. T. Holgate 1. Twelve healthy young men took part in this investigation of the effect of oral theophylline and dipyridamole (two drugs known to affect the pharmacological effects of the purine nucleoside adenosine) on the respiratory response...
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Clin Sci (Lond) (1990) 79 (2): 131–138.
Published: 01 August 1990
...Anders Edlund; Alf Sollevi; Birgitta Linde 1. Haemodynamic and metabolic effects of intravenous infusion of adenosine, an endogenous vasodilator, were studied in healthy humans. 2. Catheters were inserted into pulmonary and brachial arteries and into the hepatic and subclavian veins. Cardiac output...
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Clin Sci (Lond) (1990) 78 (1): 25–31.
Published: 01 January 1990
...T. L. Griffiths; S. J. Warren; A. D. B. Chant; S. T. Holgate 1. We have studied the carotid body contribution to hypoxic respiratory drive, using a hypoxic/hyperoxic switching technique, and the ventilatory response to intravenous infusion of adenosine, a recently described respiratory stimulant...
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Clin Sci (Lond) (1986) 70 (5): 461–468.
Published: 01 May 1986
...Jonathan S. Mann; Andrew G. Renwick; Stephen T. Holgate 1. Human leucocytes whose adenine nucleotide pool was prelabelled with [ 3 H]adenine were investigated for their capacity to release adenosine and its metabolites and histamine when activated with the calcium ionophore A23187...
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Clin Sci (Lond) (1986) 70 (4): 353–357.
Published: 01 April 1986
...Elizabeth A. Woodcock; Edward Leung; Colin I. Johnston 1. Adenylate cyclase activity in homogenates of human papillae was stimulated by adenosine agonist compounds. 2. The rank order of agonist potencies for stimulation was 5′- N -ethylcarboxamidoadenosine > l - N 6 -phenylisopropyladenosine...
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