...Karla Bianca Neves; Núbia S. Lobato; Rhéure Alves Moreira Lopes; Fernando P. Filgueira; Camila Ziliotto Zanotto; Ana Maria Oliveira; Rita C. Tostes The adipokine chemerin has been implicated in cardiovascular complications associated with obesity and the metabolic syndrome. Chemerin has direct...

... adipocyte adipokine fructose-rich diet insulin signalling lipid metabolism metabolic syndrome • The current epidemics of obesity, Type 2 diabetes and the MS could be ascribed to the drastic increase in fructose consumption. On the other hand, administration of an FRD to normal rats induces...

... to the inflammation pathways in diabetic nephropathy include transcription factors, pro-inflammatory cytokines, chemokines, adhesion molecules, Toll-like receptors, adipokines and nuclear receptors, which are candidates for the new molecular targets for the treatment of diabetic nephropathy. Understanding...

... Journal compilation © 2012 Biochemical Society 2012 adipokine atherosclerosis hypertension obesity perivascular adipose tissue vascular contraction Before the 1980s, the importance of the endothelium in vascular biology was largely ignored. The discovery of EDRF (endothelium-derived...

... colony-enhancing factor) has recently been identified as a novel adipokine with insulin-mimetic effects. Furthermore, an enzymatic function has been reported that reveals visfatin/PBEF as Nampt (nicotinamide phosphoribosyltransferase; EC 2.4.2.12.). Moreover, reports on the structure and hormonal...

...Weidong Zhu; Kenneth K. Y. Cheng; Paul M. Vanhoutte; Karen S. L. Lam; Aimin Xu Adiponectin is a major adipocyte-secreted adipokine abundantly present in the circulation as three distinct oligomeric complexes. In addition to its role as an insulin sensitizer, mounting evidence suggests...

... is now recognized to be complex. Adipose-tissue factors play a central role in the control of energy balance and whole-body fuel homoeostasis. The regulation of adipose-tissue function, in particular its secretion of adipokines, is impaired by increases in adipose mass associated with obesity...