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Keywords: adipokines
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Articles
Clin Sci (Lond) (2021) 135 (6): 731–752.
Published: 17 March 2021
... change is the dysregulation of adipokine production. Adipokines are an indispensable link between metabolism and optimal immune system function; however, their dysregulation in obesity contributes to chronic low-grade inflammation and disease pathology. Herein, I will highlight current knowledge...
Articles
Clin Sci (Lond) (2020) 134 (1): 3–13.
Published: 03 January 2020
... with resistin, an adipokine that was shown to increase the permeability of endothelial cells in vitro , shedding light on the multiple mechanisms whereby PVAT may contribute to the pathogenesis of atherosclerosis [ 20 , 21 ]. The location of PVAT, abutting the nearby adventitia of blood vessels without...
Articles
Clin Sci (Lond) (2019) 133 (22): 2329–2344.
Published: 28 November 2019
... multiple cell types whose collective secretome, termed as adipokines, is highly interdependent on metabolic homeostasis and inflammatory state. Anatomical location (e.g. visceral, subcutaneous, epicardial etc) and cellular composition of adipose tissue (e.g. white, beige, and brown adipocytes, macrophages...
Articles
Clin Sci (Lond) (2019) 133 (22): 2317–2327.
Published: 26 November 2019
... as an endocrine organ, secreting soluble factors termed adipocytokines or adipokines. These adipokines play crucial roles in whole-body metabolism with different mechanisms of action largely dependent on the tissue or cell type they are acting on. The pancreatic β cell, a key regulator of glucose metabolism due...
Articles
Clin Sci (Lond) (2017) 131 (13): 1529–1540.
Published: 28 June 2017
...-inflammatory adipokines in PE and healthy pregnancy. Subcutaneous and visceral adipose tissue biopsies were collected from healthy ( n =13) and PE ( n =13) mothers. Basal and lipopolysaccharide (LPS) stimulated adipocyte TNFα, IL-6, CCL-2, and CRP release was measured. Adipose tissue cell densities...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2016) 130 (18): 1603–1614.
Published: 08 August 2016
... (email bluma@medizin.uni-leipzig.de ). 14 1 2016 31 5 2016 2 6 2016 © 2016 The Author(s). published by Portland Press Limited on behalf of the Biochemical Society 2016 adipocytes adipokines adipose tissue inflammation adipose tissue macrophages insulin resistance...