... of a commercial ELISA kit (2-CAT (A-N) Research ELISA™, LDN, Nordhorn, Germany). adrenergic receptor liver cirrhosis portal hypertension temperature The α-adrenergic pathway has been shown to be involved in cirrhosis and portal hypertension. Prazosin, an α-adrenergic antagonist, has been shown...

... adrenergic receptor density, G protein-coupled receptor kinase 2 (GRK2) and the putative role of nitric oxide (NO). Sepsis was induced in female mice by cecal ligation and puncture (CLP). Wildtype mice were treated with prazosin 12 h after CLP or nitric oxide synthase 2 (NOS-2) inhibitor, 30 min before and 6...

... adaptation [ 24 ]. Upon cold exposure, catecholamines [in particular, noradrenaline (norepinephrine)] released by the sympathetic nerves act on adrenergic receptors in BAT and activates adenylate cyclase to increase intracellular cAMP levels, which then trigger activation of PKA (cAMP-dependent protein...

... Values are means±S.E.M. * P <0.05 compared with saline control (Con), as determined using Student's t test ( n =10). The Biochemical Society 2004 adrenergic receptor arterial pressure autonomic nervous system positive-pressure ventilation systolic pressure The regulation...