... against cardiac mitochondrial dysfunction, preserving mitochondrial phosphorylation capacity and attenuating DOX-induced decreased tolerance to MPTP opening. adriamycin apoptosis doxorubicin (DOX) exercise mitochondrial bioenergetics mitochondrial permeability transition pore (MPTP) DOX...

...Gian Marco Ghiggeri; Fabrizio Ginevri; Giovanni Cercignani; Roberta Oleggini; Alessando Garberi; Giovanni Candiano; Paola Altieri; Rosanna Gusmano 1. A low protein diet prevents the development of proteinuria and glomerular damage in adriamycin experimental nephrosis without affecting renal...

... in puromycin aminonucleoside and adriamycin experimental nephrosis by generating uric acid from hypoxanthine and xanthine. 2. The concentrations in renal tissue of the putative intermediary products of puromycin aminonucleoside metabolism, hypoxanthine and xanthine, and of their precursors, adenosine...

.... For this purpose, we studied the effects of captopril (a thiol-containing angiotensin converting enzyme inhibitor), enalapril (an angiotensin converting enzyme inhibitor without a thiol group) and cysteine (a thiol-containing amino acid which has no angiotensin converting enzyme-inhibitory action) in adriamycin...

...Seiya Okuda; Kenichi Motomura; Tohru Sanai; Hideki Hirakata; Fumio Nanishi; Kaotu Onoyama; Masatoshi Fujishima 1. We examined the effects of various levels of dietary protein on the course of adriamycin-induced nephropathy in rats fed with high (30%), intermediately low (10%) or strictly low (5...

... of adriamycin (ADR). Serial changes of urinary protein, blood pressure and blood chemistry for 22 weeks after ADR-treatment, and renal histology at week 22, were compared between ADR-treated SHR (group ADR-HT) and ADR-treated SHR given antihypertensive drugs (group ADR-AH). 2. Hypertension persisted in group...