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Keywords: aldosterone blockade
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Clin Sci (Lond) (1992) 83 (4): 467–475.
Published: 01 October 1992
... alone increased blood pressure by 7% ( P <0.05), decreased effective renal blood flow markedly and reduced urine flow and osmolar and free water clearances. Na + and K + excretion did not change significantly. Aldosterone blockade with canrenoate increased Na + excretion by a factor of 10; subsequent...