...S. J. IQBAL; D. S. PLAHA; G. H. LINFORTH; R. DALGLEISH Hypophosphatasia is a rare disease characterized by low serum levels of tissue non-specific alkaline phosphatase (TNSALP) and a spectrum of skeletal disease varying from the severest form with death in utero to mild with no clinical abnormality...

...Peter R. Gibson; Diana Kilias; Ourania Rosella; Jenny M. Day; Margaret Abbott; Caroline F. Finch; Graeme P. Young 1. This study aimed to determine the effect of luminal butyrate on proliferative kinetics, a differentiation marker (alkaline phosphatase), and a molecule that controls cell-substratum...

... to their menopausal status. However, postmenopausal thyroidectomized patients showed significantly lower bone mass ( P < 0.001) than premenopausal patients. 3. L-Thyroxine-treated patients showed significantly higher levels of bone alkaline phosphatase and urine hydroxyproline excretion than control subjects ( P...

... and alkaline phosphatase) that originate in renal proximal tubular cells. 2. Studies were performed on 118 non-insulin-dependent diabetic patients, 59 non-diabetic patients with chronic renal disease and 47 normal control subjects. First, the correlation between renal function, glycaemic control and urinary...

... 4 1990 4 5 1990 © 1990 The Biochemical Society and the Medical Research Society 1990 alkaline phosphatase gastrointestinal neoplasms leucocytes muscles zinc Clinical Science (1990) 79,247-252 247 Cellular and muscle zinc in surgical patients with and without gastrointestinal...

... that on maternal iron status was slower. 3. There was no parallel decrease of zinc concentration in maternal mixed leucocytes, or of plasma heat-labile alkaline phosphatase activity, suggesting that there was a redistribution of zinc between plasma and tissues. 4. The results indicate that iron supplementation...

..., namely the bone-specific vitamin-K-dependent protein osteocalcin, and the enzyme alkaline phosphatase. Although stanozolol tended to increase the values, this was not seen in all experiments. 4. We conclude that human bone cells respond to stanozolol. The effects of this agent on cell proliferation may...

...M. Gilles-Baillien; P. G. Carlier; G. L. Rorive 1. Alkaline phosphatase, sucrase, Na + , K + -ATPase and Mg 2+ -ATPase specific activities of crude membrane fractions, prepared from duodenal, jejunal, ileal and colonic mucosa, have been estimated in three types of hypertensive rats...

... activities of key enzymes implicated in HCO − 3 secretion may reflect the biochemical basis for the decreased mucosal resistance. 2 7 1982 27 9 1982 © 1983 The Biochemical Society and the Medical Research Society 1983 adenosine triphosphatase alkaline phosphatase bicarbonate brush...

... in the normal adults and was inversely related to plasma alkaline phosphatase activity ( r = −0.55, n = 24, P <0.001). 3. When the patients with Paget's disease were treated with either diphosphonate or calcitonin, the plasma α 2 HS-glycoprotein concentration increased towards normal. In those patients...

...R. G. Crilly; M. M. Jones; A. Horsman; B. E. C. Nordin 1. Plasma alkaline phosphatase activity and urine hydroxyproline excretion were measured in age-matched premenopausal and postmenopausal women. 2. Both measurements were found to be significantly higher in postmenopausal women. 3...

... compared with the other fractions. In addition the equilibrium densities of the various organelles in these cells were lower than those from parenchymal cells. 16 1 1978 30 5 1978 © 1978 The Biochemical Society and the Medical Research Society 1978 alkaline phosphatase biliary tract...

... exposed latent alkaline phosphatase activity in jejunal enterocytes and indicated that this enzyme is present not only in the brush border but also in the basal-lateral membrane and soluble fractions of the cell. 4. Isolated jejunal brush-border preparations showed latent activities of both alkaline...

...A. M. Wootton; G. Neale; D. W. Moss 1. The distribution of three membrane-bound enzymes, alkaline phosphatase, 5′-nucleotidase and γ-glutamyl transferase, has been examined in rat liver fractionated into parenchymal cells, a Kupffer cell fraction and a biliary tract fraction by perfusion...

...G. E. Levin; C. K. McPherson; Patricia M. Fraser; D. N. Baron 1. Plasma aspartate transaminase and alkaline phosphatase activities were measured weekly for approximately 30 weeks in a group of healthy males and females. 2. The magnitude of variation of the enzyme activities within any individual...