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Keywords: amino acid
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Clin Sci (Lond) (2022) 1117–1137.
Published: 05 August 2022
... unclear, dysregulation of placental function is implicated. We hypothesised that maternal infection, leading to maternal immune activation and stimulated cytokine production, alters placental and yolk sac amino acid transport, affecting fetal brain development and thus NDD risk. Using a rat model...
Includes: Supplementary data
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Clin Sci (Lond) (2010) 119 (11): 465–466.
Published: 17 August 2010
... Toth M. J. LeWinter M. M. Ades P. A. Matthews D. E. Impaired muscle protein anabolic response to insulin and amino acids in heart failure patients: relationship with markers of immune activation Clin. Sci. 2010 119 467 476 14 Anker S. D. Chua T. P. Ponikowski P...
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Clin Sci (Lond) (2007) 113 (7): 313–318.
Published: 03 September 2007
...Bo Westman; Lars Weidenhielm; Olav Rooyackers; Katarina Fredriksson; Jan Wernerman; Folke Hammarqvist The temporal pattern of metabolic alterations in muscle tissue during total ischaemia and reperfusion are not well-characterized in humans with respect to glutathione, amino acids and energy-rich...
Includes: Supplementary data
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Clin Sci (Lond) (2007) 112 (10): 527–532.
Published: 12 April 2007
... with an attenuated acute-phase response. This indicates that altered arginine metabolism may be an important characteristic of the metabolic changes in cancer. amino acid arginine cancer metabolism nitric oxide stable isotope surgery We have described recently [ 1 ] that patients with malignant...
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Clin Sci (Lond) (2005) 109 (6): 523–530.
Published: 23 November 2005
... in endothelial dysfunction in CHF. In that study [ 18 ], we found that the expression of the system y + cationic amino acid transporter CAT-1 was reduced, providing a potential explanation for reduced L -arginine transport in CHF. To further define the role of L -arginine transport in the setting...
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Clin Sci (Lond) (2003) 105 (2): 213–218.
Published: 01 August 2003
... (CFS), a disorder characterized chiefly by persistent, often debilitating, fatigue. We wished to characterize circulating profiles of putative amino acid modulators of CNS 5-hydroxytryptamine (5-HT; serotoninergic) and dopaminergic function in CFS patients at rest, as well as during symptom-limited...
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Clin Sci (Lond) (1997) 92 (4): 423–430.
Published: 01 April 1997
... or received three meals at 9.00 hours, 13.00 hours and 18.00 hours. Catecholamines and metabolites were determined by reverse-phase HPLC with electrochemical detection. Neutral amino acids were measured by ionexchange chromatography with photometric detection. 3. The food contained relatively little DOPA...
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Clin Sci (Lond) (1989) 76 (4): 419–422.
Published: 01 April 1989
...). A similar increase in V max. in uraemic cells compared with controls was seen in erythrocytes which were studied in zero-trans conditions after depletion of intracellular amino acids. The mean values of K m and K D were not significantly different in uraemia. The origins of this increased membrane transport...
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Clin Sci Mol Med (1977) 52 (3): 311–318.
Published: 01 March 1977
... 10 1976 © 1977 The Biochemical Society and the Medical Research Society 1977 amino acid glucose Huntington's chorea insulin provocation test non-esterified fatty acids tryptophan Clinical Science and Molecular Medicine (1977) 52, 3 11-3 18. Plasma glucose, non-esterified fatty...
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Clin Sci Mol Med (1976) 50 (6): 525–532.
Published: 01 June 1976
... of a labelled essential amino acid would therefore give more accurate values for short-term measurements of whole body protein turnover. 14 7 1975 © 1976 The Biochemical Society and the Medical Research Society 1976 amino acid protein [ 14 C]tyrosine Clhical Science and Molecular Medicine...
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