... epithelium of the human placenta, and decreased expression of amino acid transporter isoforms in the ST plasma membranes is believed to contribute to IUGR. Placental mechanistic target of rapamycin Complex 2 (mTORC2) signaling is inhibited in IUGR and regulates the trafficking of key amino acid transporter...

... -arginine may thus be important for subsequent polyamine-dependent proliferation. In the present study we investigated radiolabelled cationic amino-acid transport in cultured PTEC exposed to 20 mg/ml ultrapure recombinant human albumin, describing the specific kinetic characteristics of transport...

... in the cystinuric patients. 5. In the heterozygous subjects the slope of the titration curves and the depression of the tubular reabsorption were intermediate between those of the control and homozygous subjects. Key words: amino acid transport, cystine, cystinuria. Introduction Cystinuria is an hereditary disorder...

... by the mucosal cell by a mechanism independent of the amino acid-transport system. 3. The presence of free amino acids in the lumen during perfusion of both dipeptides suggests that hydrolysis occurs at some stage in the uptake process. Intraluminal hydrolysis was insufficient to account for the concentration...

... confirm the existence of dipeptide transport systems independent of those for free amino acids. 25 4 1972 © 1972 The Biochemical Society and the Medical Research Society 1972 amino acid transport dipeptide transport cystinuria Clinical Science (1972) 43,659-668. INTESTINAL DIPEPTIDE...