...Cristina A. Teixeira; Maria do Rosário Almeida; Maria João Saraiva Transthyretin (TTR)-related amyloidoses are diseases characterized by extracellular deposition of amyloid fibrils and aggregates in tissues composed of insoluble misfolded TTR that becomes toxic. Previous studies have demonstrated...

...Philip N. Hawkins 1. Quantitative scintigraphic and turnover studies, utilizing the specific binding affinity of serum amyloid P component for amyloid fibrils, have been developed as a tool for evaluating amyloid deposits in vivo. 2. Serial studies in over 300 patients have shown characteristic...

...D. L. Scott; P. Bracken; P. A. Bacon; G. Husby 1. The clarification of turbid AA-amyloidfibril-containing agarose gels by serum has been ascribed to degradation of the fibrils and designated as ‘amyloid degrading factor'. In the present study, sera of 32 healthy blood donors and 32 patients...