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Keywords: amyloidosis
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Articles
Clin Sci (Lond) (2000) 98 (4): 427–433.
Published: 24 March 2000
... myeloma and as a marker of renal function, and has been shown to be involved in the pathogenesis of dialysis-related amyloidosis. α 2 -Macroglobulin has the ability to bind a wide range of physiologically important molecules, thereby influencing their metabolic impact. In this study we show by Western...
Articles
Clin Sci (Lond) (1994) 87 (5): 487–491.
Published: 01 November 1994
...S. Y. Tan; I. E. Murdoch; T. J. Sullivan; J. E. Wright; Oanh Truong; J. J. Hsuan; P. N. Hawkins; M. B. Pepys 1. Primary orbital amyloidosis is a rare form of localized amyloidosis in which the precursor protein has not previously been identified. We report here the first extraction of amyloid...
Articles
Clin Sci (Lond) (1994) 87 (3): 289–295.
Published: 01 September 1994
..., diagnostic tissue distributions of amyloid in different types of amyloidosis. There is generally a poor correlation between quantity of amyloid and associated organ dysfunction. 3. Contrary to previous expectations, regression of amyloid has been demonstrated systematically for the first time: AA, AL and...
Articles
Clin Sci (Lond) (1989) 76 (5): 547–552.
Published: 01 May 1989
... in haemodialysis-associated amyloidosis, and also suggest a possible role for α 2 -microglobulin: it may protect β 2 -microglobulin from proteolytic digestion, leading to its accumulation in intact form and to amyloid fibril formation. 15 8 1988 4 10 1988 © 1989 The Biochemical...
Articles
Clin Sci (Lond) (1987) 73 (5): 515–518.
Published: 01 November 1987
... clearly present in the amyloid material, they were not accessible for sequence determination. The identification of the other protein constituents present in the amyloid material, along with β 2 M, should provide a better understanding of haemodialysis-associated amyloidosis, the mechanisms of formation...