... and -degrading processes [4] occur in plasma and tend to hamper accurate analysis. Finally, highly sensitive and specific antibodies and efficient extraction procedures are required for valid measurement of plasma kinins. Key words angiotensin I, angiotensin 11, angiotensin-converting enzyme activity...

... with polyacrylamide beads and superfusion with oxygenated physiological medium. 3. Renin was detected in the superfusate by incubation of fractions with excess nephrectomized sheep substrate in the presence of angiotensinase inhibitors followed by radioimmunoassay of the angiotensin I generated. 4. Optimized...

... with angiotensin I, angiotensin II or synthetic hog tetradecapeptide renin substrate. However, rat des-angiotensin I—angiotensinogen cross-reacted 100% with the angiotensinogen antibody. 2. A direct radioimmunoassay for rat angiotensinogen in plasma was developed and this enabled 5 fmol of this protein...

... in human cerebrospinal fluid is an immunoassay artifact © 1980 The Biochemical Society and the Medical Research Society 1980 angiotensin I angiotensin II renin renin substrate Clinical Science ( 1980) 59,6 1 s-64s 61s Angiotensin I1 in human cerebrospinal fluid may be an immunoassay artifact...

...Th. Unger; R. W. Rockhold; K. Schaz; P. Vescei; G. Bönner; W. Rascher; D. Ganten 1. The effects of long-term treatment with the angiotensin I converting-enzyme inhibitor YS 980 were examined in stroke-prone spontaneously hypertensive (sp-SH) rats. Development of hypertension was markedly blunted...

... angiotensin I kidney renin Clinical Science and Molecular Medicine [ 1977) 53, 189-191. SHORT COMMUNICATION Evidence that inactive renin is produced outside the kidney of the rat R. VANDONGEN, MARIANNE POESSeE, K. D . STRANG AND W. H. BIRKENHWGER Department of Internal Medicine, Zuiderziekenhuis...

... flow suggests a direct effect on the renin-producing cell. © 1976 The Biochemical Society and the Medical Research Society 1976 angiotensin I diazoxide frusemide renal vasodilators renin secretion Clinical Science and Molecular Medicine ( I 976) 51, 10 I S-1 04s. Stimulation of renin...

...D. R. Bangham; Iris Robertson; J. I. S. Robertson; C. J. Robinson; M. Tree © 1975 The Biochemical Society and the Medical Research Society 1975 angiotensin I angiotensin II bioassay radioimmunoassay renin renin-substrate Clinical Science and Molecular Medicine (1975) 48, 135s-I 59s...

... propranolol phenoxybenzamine noradrenaline angiotensin I Clinical Science and Molecular Medicine (1974) 47,471479. THE INHIBITION O F RENIN SECRETION BY ALPHA-ADRENERGIC STIMULATION I N THE ISOLATED RAT KIDNEY R. VANDONGEN AND W. S. PEART Medical Unit, St Mary s Hospital Medical School, London (Received...

...K. G. Hofbauer; H. Zschiedrich; W. Rauh; F. Gross 1. In the isolated rat kidney, perfused at constant pressure with a medium free from renin substrate, addition of angiotensin I to the perfusate decreases renal ‘plasma’ flow. 2. A peptide inhibitor, SQ 20881, of converting enzyme reduces...

...S. Fukuchi; T. Takeuchi; T. Torikai 1. A simple, rapid radioimmunoassay of angiotensin I has been applied to the measurement of plasma renin activity. 2. Antibody to angiotensin I was raised in rabbits by injecting angiotensin I conjugated with rabbit serum albumin. 3. Angiotensin I was generated...