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Keywords: animal model
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Articles
Clin Sci (Lond) (2016) 130 (3): 127–150.
Published: 17 December 2015
... to manage PAD which can be applied to patients unlikely to benefit from interventional approaches. Many of the therapeutic agents successful in inducing angiogenesis and arteriogenesis in pre-clinical animal models of PAD have failed to have efficacy in human randomized control trials. One possible reason...
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Clin Sci (Lond) (2014) 127 (11): 615–634.
Published: 25 July 2014
... of restenosis, which remains a clinically relevant problem. Biomedical research in pre-clinical animal models of (re)stenosis, despite its limitations, has contributed enormously to the identification of processes involved in restenosis progression, going well beyond the initial dogma of a primarily...
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Clin Sci (Lond) (2014) 127 (4): 209–216.
Published: 10 April 2014
... and increased age, the strongest risk factor is obesity. The aim of the present review is to focus on three cutting-edge topics with respect to OSA. The section on animal models covers various strategies used to simulate the physiology or the effects of OSA in animals, and how these have helped to understand...
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Clin Sci (Lond) (2013) 124 (6): 391–401.
Published: 27 November 2012
... phosphatase 1 catalytic subunit β-isoform) were quantified by real-time PCR. Results were computed with specialized software (qBase plus; Biogazelle) and given as the ratio between the gene of interest and the housekeeping gene HMBS (hydroxymethylbilane synthase). animal model echocardiography...
Includes: Supplementary data
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