... increasingly unresponsive and apparently disappear, owing to several possible mechanisms, such as escape mutations in critical viral epitopes, lack of sufficient help, clonal anergy or expansion of regulatory T-cells. The role of neutralizing antibodies remains uncertain, although it is still possible...

...Jianguo Shi; Richard S. Mcintosh; Richard J. Pleass Abs (antibodies) are complex glycoproteins that play a crucial role in protective immunity to malaria, but their effectiveness in mediating resistance can be enhanced by genetically engineered modifications that improve on nature. These Abs also...

... were from a Swedish population-screening programme (diastolic pressure <80 mmHg). The presence of carotid atherosclerosis and the intima-media thicknesses were determined by ultrasonography. A monoclonal antibody to OxLDL, EO6, was used to determine oxidation epitopes in LDL. aOxLDL of IgG and IgM...

... antibody cytotoxic T lymphocyte. 475Clinical Science (2002) 102, 475 486 (Printed in Great Britain) + R E V I E W The immunopathogenesis of paraneoplastic neurological syndromes Ian SUTTON and John B. WINER Department of Neurology, Queen Elizabeth Hospital, Edgbaston, Birmingham B15 2TH, U.K. A B S T R...

.... The absence of such complexes does not mean that previous interaction with enzyme has not occurred, thereby accounting for a reduction in α 1 AT inhibitory capacity. 23 6 1983 2 8 1983 © 1984 The Biochemical Society and the Medical Research Society 1984 antibody α 1 -antitrypsin...

... in lung secretions. Key words: antibody, al-antitrypsin, leucocyte elastase, lung secretions, proteolysis. Correspondence: Dr R. A. Stockley, The General Hospital, Steelhouse Lane, Birmingham B4 6NH, U.K. Abbreviations: q A T , al-antitrypsin; 2DIEP, two- dimensional immunoelectrophoresis; LE, leucocyte...

...E. Hackenthal; H. Bauknecht; P. Oster 1. Antibodies against angiotensin II were purified by affinity chromatography. 2. When injected intravenously into rats, the antibody distributed in the extracellular space with a half-time of 11 h and a distribution volume of about 10 ml/100 g body weight...

...’ was associated with precipitating antibody to BSA, with rapid removal of antigen, and with the appearance of fibrin microthrombi in the renal glomeruli. It also appeared to be related to the development of proliferative glomerular histology. Further, inhibition of fibrinolysis before antigen challenge may lead...