... aortopathy nicotine sex hormones Abdominal aortic aneurysms (AAAs) represent a critical health risk characterized by the abnormal dilation of the abdominal aorta, which often remains asymptomatic until reaching a critical size with a high propensity to rupture [ 1 ]. AAAs are insidious, potentially...

... with the congenital bicuspid malformation of the aortic valve (BAV). Dysregulated autophagy in response, for example, to wall shear stress alterations, has been demonstrated to affect the phenotype of vascular cells relevant to aortopathy, with potential consequences on signaling, remodeling, and angiogenesis...