... -Arginine transport via system y + L, but not y + , was significantly reduced in RBCs from hypertensive patients (60±7 μmol·l −1 ·cells −1 ·h −1 ; n =16) compared with controls (90±17 μmol·l −1 ·cells −1 ·h −1 ; n =18). In human platelets, the V max for L -arginine transport via system y + L was 86±17 pmol...

..., and this effect was maximal when a lower concentration was used (10 μ M compared with 40 μ M). In order to explore additional effects of allicin on NO generation that might counteract the effect on iNOS, we assessed the effects of higher allicin concentrations on arginine transport. Allicin inhibited the uptake...

... was mediated by the classical cationic amino acid transport systems y + and y + L. 3. The V max for l-arginine transport via system y + increased from 292 to 490 μmol h −-1 l −-1 of cells in heart failure. 4. With system y + inhibited by N -ethylmaleimide (0.2 mmol/l), the V max for the transport of l-arginine...

... values after dialysis. 3. Saturable influx of l-arginine was mediated by the classical cationic amino acid transport system y+ and system y+L, known to transport cationic and neutral amino acids with higher affinity. 4. Under zero- trans conditions, the V max for l-arginine transport via system y...