... 12 2 2007 artery blood pressure central nervous system dopamine receptor hypertension kidney sodium homoeostasis Essential hypertension affects 25% of the adult population and constitutes a major risk factor for stroke, myocardial infarction, heart failure and kidney failure...

... are important regulators of vascular tone and may therefore contribute to this hyperaemia. The aim of the present study was to determine the contribution of NO and vasodilator prostanoids to this skeletal muscle hyperaemia in diabetes. We assessed the effects of infusion into the intrabrachial artery...

...S. J. Bund; A. Tweddel; I. Hutton; A. M. Heagerty 1. There is increasing evidence that a substantial number of patients who suffer from angina have normal epicardial arteries (Syndrome X), and it has been suggested that these individuals have a generalized disorder of small vessels not confined...

... of high shear and endothelial damage (the Folts model of intracoronary thrombosis) we used the specific thrombin inhibitor recombinant hirudin. 2. A critical coronary artery stenosis overlying an area of crushed endothelium was used in a repeated measures study of eight open-chest anaesthetized dogs...

...M. Barradas; M. Khokher; R. Hutton; I. L. Craft; P. Dandona 1. The degradation of ADP by the placenta and umbilical artery was investigated. 2. Supernatants from incubations of finely chopped placental and umbilical arterial tissue were incubated with [ 14 C]ADP for various durations from 0 to 30...

...Anne-Marie Moura; Manuel Worcel 1. Aldosterone given acutely to male Wistar rats stimulated ouabain-sensitive and ouabain-insensitive 22 Na efflux from tail arteries. 2. These effects of aldosterone seem to depend on the activation of specific mineralocorticoid receptors, as they are blocked...

...Héctor Nolly; M. Cristina Lama 1. The present study was undertaken to examine whether there is a kallikrein-like enzyme in vascular tissue. Isolated saline-perfused rat mesenteric arteries were used and arterial homogenate was incubated with heat-treated dog plasma and citrate/phosphate buffer (pH...

...R. D. S. Watson; A. J. F. Page; W. A. Littler; D. H. Jones; J. L. Reid 1. Blood samples were obtained simultaneously from femoral artery and vein, pulmonary artery and antecubital vein at rest and during isometric and dynamic exercise in six patients during cardiac catheterization and plasma...

...C. Rosendorff; D. S. Bloom; M. G. Stein 1. The noradrenaline sensitivity of the isolated perfused rabbit artery was studied, during perfusion with Krebs solution, normal plasma, hypertensive plasma and a low-density lipoprotein (LDL) extract of normal plasma. 2. There was no difference...