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Keywords: atrasentan
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Articles
J. Ruth WU-WONG, Douglas B. DIXON, William J. CHIOU, Brian K. SORENSEN, Gang LIU, H.-S. JAE, Andrew TASKER, Thomas W. Von GELDERN, Martin WINN, Terry J. OPGENORTH
Journal:
Clinical Science
Clin Sci (Lond) (2002) 103 (s2002): 107S–111S.
Published: 01 September 2002
... September 2001 Dr J.R. Wu-Wong, Abbott Laboratories, 5440 Patrick Henry Drive, Santa Clara, CA 95054, U.S.A. (e-mail [email protected] ). © 2002 The Biochemical Society and the Medical Research Society 2002 A-182086 A-192621 ABT-546 ABT-627 atrasentan endothelin endothelin...
Articles
Jerry L. WESSALE, Andrew L. ADLER, Eugene I. NOVOSAD, Samuel V. CALZADILLA, Brian D. DAYTON, Kennan C. MARSH, Martin WINN, Hwan-Soo JAE, Thomas W.von GELDERN, Terry J. OPGENORTH, J. Ruth WU-WONG
Journal:
Clinical Science
Clin Sci (Lond) (2002) 103 (s2002): 112S–117S.
Published: 01 September 2002
... A and ET B receptors to initiate their effects. Based on the same core structure, we have developed four small-molecule ET receptor antagonists, ABT-627 (atrasentan), ABT-546, A-182086 and A-192621, which exhibit differences in selectivity for ET A and ET B receptors. In this report, we compare...
Articles
Mélanie GOSSELIN, Stéphanie GOULET, Jinshyun R. WU-WONG, Jerry L. WESSALE, Terry J. OPGENORTH, Louis-Philippe BOULET, Bruno BATTISTINI
Journal:
Clinical Science
Clin Sci (Lond) (2002) 103 (s2002): 367S–370S.
Published: 01 September 2002
... expression of ET A receptors in these two murine strains, or in post-receptor transduction modulation, or different regulation of ET receptors in various pulmonary cells, after sensitization and challenge. Balb/c mouse C57Bl/6 mouse endothelin A receptor antagonist atrasentan The Seventh...
