... 2007 and May 2013 with a diagnosis of chronic autonomic failure were included in the present study if they met the criteria for neurogenic OH [SBP drop ≥ 20 mmHg (or ≥30 mmHg if the supine SBP was ≥160 mmHg) or DBP drop ≥ 10 mmHg; 1] and had undergone autonomic function testing which included...

.... Correspondence: Dr Wouter Wieling (e-mail [email protected] ). 5 3 2001 8 6 2001 25 7 2001 The Biochemical Society and the Medical Research Society © 2001 2001 ambulatory blood pressure autonomic failure finger blood pressure orthostatic tolerance pulse contour analysis...

...P. CARIGA; C. J. MATHIAS Oral water ingestion increases blood pressure in normal elderly subjects and in patients suffering from autonomic failure, but the time course of the haemodynamic changes is not known. We therefore studied 14 subjects with documented sympathetic denervation due to pure...

...W. Wieling; J. J. Van Lieshout; A. D. J. Ten Harkel 1. The initial circulatory adjustments induced by head-up tilt and tilt-back were investigated in six healthy subjects (aged 30–58 years) and six patients with orthostatic hypotension due to pure autonomic failure (aged 33–65 years). 2. Continuous...

...G. D. P. Smith; M. Alam; L. P. Watson; C. J. Mathias 1. In autonomic failure, supine exercise lowers blood pressure and worsens postural hypotension. The somatostatin analogue, octreotide, reduces postprandial and postural hypotension, but its effects on exercise-induced hypotension and on postural...

.... In contrast, in the patients an increase in cardiac output (16 ± 12%) and mean blood pressure (13 ± 13 mmHg) was observed. 4. Tiptoeing and leg-crossing have different effects on orthostatic blood pressure in healthy adult subjects and in patients with autonomic failure. In normal humans, tiptoeing increases...

... prevent postprandial hypotension in symptomatic elderly patients. © 1994 The Biochemical Society and the Medical Research Society 1994 ageing autonomic failure blood pressure splanchnic circulation syncope Clinical Science (1994) 87. 259-267 (Printed in Great Britain) 259 Haemodynamic...

...-cutaneously), in seven patients with chronic autonomic failure 2. In the placebo phase, after glucose, there was a marked and prolonged fall in blood pressure with no change in cardiac index and peripheral blood flow. Plasma insulin and neurotensin levels increased, whereas glucagon, vasoactive intestinal...

...C. J. Mathias; D. F. da Costa; C. M. McIntosh; P. Fosbraey; R. Bannister; S. M. Wood; S. R. Bloom; N. J. Christensen 1. To investigate whether carbohydrate contributes to postprandial hypotension in autonomic failure, the cardiovascular, biochemical and hormonal effects of oral glucose and an iso...

...R. S. Kirby © 1986 The Biochemical Society and the Medical Research Society 1986 autonomic failure cholinergic dysautonomia incontinence pandysautonomia Clinical Science (1986) 70 (Suppl. 14), 45s-50s 45s Autonomic failure and the role of the sympathetic nervous system in the control...

...T. D. M. Williams; D. DaCosta; C. J. Mathias; R. Bannister; S. L. Lightman 1. The blood pressure (BP) and heart rate (HR) responses to 5 min incremental intravenous infusions of noradrenaline (NA) and arginine vasopressin (AVP) were investigated both in patients with progressive autonomic failure...

...-selective β-adrenoceptor agonist isoprenaline, the β 2 -selective agonist salbutamol and the β 1 -selective agonist prenalterol suggests preferential β 2 -adrenoceptor sensitization in chronic autonomic failure, which can be reversed by treatment with the non-selective partial β-adrenoceptor agonist...

...C. S. Wilcox; M. J. Aminoff; J. D. H. Slater 1. The renal excretion of sodium by five patients with autonomic failure (Shy—Drager syndrome) was compared with a matched control group who had normal autonomic reflexes (Parkinson's disease). For 8 or 9 days the daily sodium intake was reduced to 17...