... ability to analyse the glomerular filtration barrier. It remains possible that podocytes exert some of their effects via the GBM (for whose synthesis podocytes are mainly responsible) and/or via interactions with GEnC. GBM glomerular basement membrane GEnC glomerular endothelial cells...

... and the Medical Research Society 1984 basement membrane Bowman's space chondroitin sulphate connective tissue proteoglycans heparin urinary glycosaminoglycans Clinical Science (1984) 67, 205-212 205 A micropuncture and renal clearance study in the rat of the urinary excretion of heparin, chondroitin...

...T. G. Cotter; G. B. Robinson 1. Filters comprising multiple layers of rabbit renal tubular basement membrane were constructed with conventional pressure filtration chambers. The effects of concentration-polarization on the behaviour of these filters was assessed by studying the filtration...

... activity at acid and neutral pH, whereas cadaver kidney showed proteinase activity at acid pH only. 3. The urine from 13 patients with glomerulonephritis showed proteinase activity at both acid and neutral pH as well as increased amounts of antigenic glomerular basement membrane fragments. The properties...

...M. Davies; A. J. Barrett; J. Travis; E. Sanders; G. A. Coles 1. Human polymorphonuclear leucocyte elastase and cathepsin G were incubated with preparations of isolated human glomerular basement membrane at neutral pH and 37°C. 2. The ability of these enzymes to degrade glomerular basement membrane...