1-2 of 2
Keywords: biased agonism
Close
Sort by
Articles
Clin Sci (Lond) (2018) 132 (21): 2323–2338.
Published: 02 November 2018
... efforts have seen mGlu 5 allosteric modulators progress into clinical trials; however, recent failures due to lack of efficacy or adverse effects indicate a need for a better understanding of the functional consequences of mGlu 5 allosteric modulation. Biased agonism is an interrelated phenomenon...
Articles
Clin Sci (Lond) (2014) 126 (11): 753–774.
Published: 13 February 2014
... and kinins. angiotensin II angiotensin II type 1 receptor (AT 1 receptor) biased agonism bradykinin G-protein-coupled receptor (GPCR) signalling pathway The term ‘vasoactive peptides’, as it literally suggests, represents a group of biologically active peptides, to which angiotensins...