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Keywords: bile
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Articles
Clin Sci (Lond) (2022) 136 (8): 639–642.
Published: 27 April 2022
... advance when published and why there is still much to be learned from this paper half a century later. 25-hydroxyvitamin D adipose bile cholecalciferol metabolism This year is the 100th anniversary of the first use of the term vitamin D to describe a fat-soluble factor that cured rickets...
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Clin Sci (Lond) (2008) 114 (9): 567–588.
Published: 02 April 2008
...Marcelo G. Roma; Fernando A. Crocenzi; Enrique A. Sánchez Pozzi The recent overwhelming advances in molecular and cell biology have added enormously to our understanding of the physiological processes involved in bile formation and, by extension, to our comprehension of the consequences...
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Clin Sci (Lond) (2002) 103 (2): 191–200.
Published: 17 July 2002
...Julia GORELIK; Sian E. HARDING; Andrew I. SHEVCHUK; Duleepa KORALAGE; Max LAB; Michael DE SWIET; Yuri KORCHEV; Catherine WILLIAMSON Obstetric cholestasis is characterized by raised bile acids, and can be complicated by intrauterine death. We have shown that the bile acid taurocholate causes loss...
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Clin Sci (Lond) (2002) 102 (6): 603–614.
Published: 30 April 2002
... in bile formation has been very limited. The hepatocyte couplet model offers a unique opportunity to study in vitro the intracellular processes involved: not only the physiology and pathophysiology of bile formation, but also the corresponding structural and molecular disturbances underlying different...
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Clin Sci (Lond) (1993) 84 (6): 675–679.
Published: 01 June 1993
... (duodenum and proximal jejunum distal to the common bile duct); SII (distal jejunum); SIII (proximal ileum) and SIV (distal ileum). 2. Cyclosporin A concentrations in whole blood were assayed by an enzyme-mediated immunoassay for up to 4 h in samples drawn from the femoral vein and used to determine...
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Clin Sci (Lond) (1989) 77 (5): 473–478.
Published: 01 November 1989
..., namely phospholipids, cholesterol and 5′-nucleotidase, into bile in anaesthetized rats receiving saline or taurocholate (0.5 μmol min −1 100 g −1 body weight) with or without protoporphyrin IX infusion (10 or 20 μg min −1 100 g −1 body weight). 2. Protoporphyrin IX induced an impairment of spontaneous...
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Clin Sci (Lond) (1984) 66 (4): 487–491.
Published: 01 April 1984
...S. Erlinger; M. Dumont; I. Zouboulis-Vafiadis; G. De Couet 1. The biliary maximum secretory rate (SR max. ) of glycoursodeoxycholate in the bile fistula anaesthetized rat was about five times that of unconjugated ursodeoxycholate. 2. Likewise, the biliary SR max. of tauro-7-ketolithocholate...
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Clin Sci Mol Med (1977) 53 (4): 373–377.
Published: 01 October 1977
... in serum, urine and bile. 2. The chromatography data indicated an excretion of 25-hydroxycholecalciferol both in bile and urine and, in urine, also of 1,25-dihydroxycholecalciferol. In bile, fractions of labelled substances were also obtained which, according to their elution positions, might represent...
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Clin Sci Mol Med (1975) 49 (3): 237–245.
Published: 01 September 1975
...-chromatography studies. 3. The nature of the copper complexes formed by secretions obtained from patients with Wilson's disease was similar to that of complexes formed by secretions of normal subjects. 4. Bile contained a copper-binding fraction of high molecular weight which was more concentrated in gall...
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Clin Sci Mol Med (1975) 49 (3): 253–256.
Published: 01 September 1975
...S. Erlinger; Dominique Bienfait; Renee Poupon; Micheline Dumont; M. Duval 1. The influence of lysine acetylsalicylate on bile flow, erythritol clearance and bile salt, phospholipid and cholesterol secretion in bile was studied in unanaesthetized dogs fitted with a Thomas duodenal cannula. 2. Lysine...
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Clin Sci Mol Med (1974) 46 (4): 433–448.
Published: 01 April 1974
...-HCC. 4. Treatment with phenobarbitone enhanced the excretion of metabolites of radioactive vitamin D 3 in bile. These metabolites were largely water-soluble conjugates of peaks IV, V and VI, which included glucuronides. Peak IV in bile was not identical with 25-HCC. 5. Prolonged treatment...
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Clin Sci Mol Med (1973) 44 (1): 9–15.
Published: 01 January 1973
...J. L. Gollan; D. J. Deller 1. Gall-bladder bile was obtained at cholecystectomy from seven patients who had been given [ 64 Cu]cupric acetate intravenously. 2. Studies using dialysis and Sephadex gel filtration indicated that most of the 64 Cu in the bile was in a heat-stable complex of molecular...
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Clin Sci (1972) 43 (3): 413–431.
Published: 01 September 1972
.... 4. Metabolically produced 25-hydroxycholecalciferol is also taken up from the blood into many tissues, probably by protein-binding. 5. Vitamin D is excreted in bile principally as more polar metabolites. Smaller amounts of cholecalciferol and 25-hydroxycholecalciferol are also excreted...